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Heterozygous BRCA1 SNPs in the Central Functional Region are Associated With ...

Yeh(MH),Li(CW),Chen(L),Shih(TY),Kang(YC),C... Clin Breast Cancer 2026-08-00

...BRCA1/2 mutations. However, certain BRCA1 single nucleotide polymorphisms may alter protein function without complete lo...

BRCA1-RAD51 homologous DNA repair pathway promotes HIV-1 reverse transcriptio...

Lapaillerie(D),Tumiotto(C),Scoca(V),Figuei... Sci Adv 2026-07-24

...BRCA1/2-dependent manner, with RAD51 loading onto viral DNA immediately during reverse transcription. Using ChIP, imagin...

Clinical and Molecular Features of BAP1-Mutated Meningiomas: Case Series.

Pradilla(I),Alfattal(R),McGovern(SL),Raza(... Mol Carcinog 2026-07-23

BRCA1-associated protein 1 (BAP1)-deficient meningiomas represent a clinically and molecularly distinct subgroup with va...

Identifying and characterizing the germinal genetic landscape of men with pro...

Svirsky(R),Sonnenfeld(B),Kedar(I),Linial(M... Genet Med Open None

...BRCA1, BRCA2, ATM, NF1, and MSH6), and 21 (7.2%) had risk allele variants. One-third (33%) of the disease-causing or lik...

Recent Advances in Genetic Testing and Clinical Management of Hereditary Brea...

Sherigar(P),Kedlaya Herga(S),Pai(A),Mailan... Cancer Med 2026-07-00

...BRCA1 and BRCA2 genes. Yet, the role of other cancer susceptibility genes highlights the genetic etiology of HBOC as com...

Navigating the Metabolic-Genomic Paradigm: Mitochondrial Reprogramming as a D...

Tzeng(YT),Wen(CY),Yong(SB),Wen(ZH),Chiang(... Oncol Res None

...BRCA1) deficiency and TP53 mutations, fundamentally reprogram mitochondrial bioenergetics. Specifically, the loss of BRC...

RAD51 in Breast Cancer: From Vulnerability to Resistance.

Anjum(RS),Takabe(K) World J Oncol 2026-08-00

...BRCA1)- and breast cancer susceptibility type 2 (BRCA2)-mutant tumors, impaired RAD51 loading produces profound sensitiv...

Integrated Bioinformatics Analysis Identifies NCAPG2 as an Immune-Related Pro...

Li(J),Wang(Q),Qiao(H) World J Oncol 2026-08-00

...BRCA1/2 mutation, and Nottingham prognostic index (NPI), while negatively correlated with age, ER status, and PR status....

Revisiting familial aggregation of prostate cancer within the 3D framework of...

Shi(K),Liang(B),He(T),Jiang(D) Mutat Res Rev Mutat Res 2026-07-23

...BRCA1/2, MLH1, HOXB13), single nucleotide polymorphisms (SNPs), germline copy number variations (GCNVs), and Y-chromosom...

From Diagnosis to Disclosure: Navigating Genetic Counseling Dilemmas in BRCA2...

van Wyk(C),Abdulrahim(R),Crous(I),Al Saegh... Case Rep Genet None

...BRCA1/2 variants, where results have therapeutic and hereditary implications. However, data from the Middle East remain ...

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