Major clinical characteristics of BRCA1/2-related cancers include association with estrogen and metabolic consequences. ...
...BRCA1/2, it is likely that measures of genomic instability and other germline biomarkers beyond BRCA1/2 may be associate...
...BRCA1 over-function via mechanism of transcription regulation in response to DNA repair. Since it was found p53 and BRCA...
...BRCA1/2 mutation carriers and non-carriers from BRCA1/2 mutation-positive families and investigated the association betw...
...BRCA1/2-mutated ovarian cancer represents the first registered indication for this class of drugs in any disease. PARP i...
...BRCA1 and TP53 (or SMAD3 and PIK3R1) being the most extensive VTP-interacting EHFs (or EHF-interacting VTPs) for HIV-1 a...
...BRCA1 associated protein-1, and are present in 10% of ccRCCs. They are largely mutually exclusive with PBRM1 mutations. ...
...BRCA1 and BRCA2 were mutated in 9.1% and 6.3%, respectively. ERCC1 and MGMT were absent in 81% and 46% of tumors analyze...
...BRCA1/2, ATM, ABL and 53BP-1/2. Most of them are nuclear proteins; however, not much is known about p53-binding transcri...
...BRCA1/2 wild-type) cells were subcutaneously injected into nude mice, which were then randomly assigned to treatment wit...
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