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TP53 BRCA1 CRISPR single-cell cancer

Ho(Jar-Yi),Hsu(Ren-Jun),Wu(Chieh-Lin),Chen... Eur J Cancer Prev 2016-04-26

...BRCA1 gene. In terms of prognosis, BRCA1 mislocalization showed a 3.5-fold (95% CI: 1.20-10.09) increased risk of breast...

Hendrikx(Jeroen J M A),Lagas(Jurjen S),Son... Int J Cancer 2016-06-01

...Brca1(F/F) ;p53(F/F) mouse mammary tumors were orthotopically implanted in syngeneic mice lacking Cyp3a (Cyp3a(-/-)) to ...

Shapira(Moran),Raanani(Hila),Feldman(Baruc... Fertil Steril 2016-02-16

...BRCA1/2 mutations and ovarian performance, as demonstrated by in vitro fertilization (IVF) outcomes.,Retrospective cohor...

Seibert(Julia K),Quagliata(Luca),Quintaval... Cancer Med 2016-09-15

...BRCA1/2 pathway and the epithelial to mesenchymal transition regulator E-cadherin were altered following DHRS7 knockdown...

Nakshatri(Harikrishna),Anjanappa(Manjushre... Sci Rep 2016-09-15

...BRCA1-mutation carriers compared with cells from healthy donors (p = 0.0014). Moreover, tumor and adjoining-normal breas...

Manié(Elodie),Popova(Tatiana),Battistella(... Int J Cancer 2016-05-31

...BRCA1/2 and other genes was also investigated. In the in-house dataset, HRD was predicted in 5% (20/385) of sporadic tum...

Ratajska(Magdalena),Matusiak(Magdalena),Ku... Oncol Rep 2016-08-08

...BRCA1 and is required for its stability and tumor-suppressor functions. In breast cancer and other epithelial cell carci...

Farasani(A),Darbre(P D) J Inorg Biochem 2016-10-11

...BRCA1 mRNA as determined by real-time RT-PCR and BRCA1 protein as determined by Western immunoblotting. Reduced levels o...

Adank(Muriel A),Hes(Frederik J),van Zelst-... Ned Tijdschr Geneeskd 2016-04-18

In the majority of breast cancer families, DNA testing does not show BRCA1 or BRCA2 mutations and the genetic cause of b...

Weaver(Alice N),Cooper(Tiffiny S),Rodrigue... Oncotarget 2016-08-15

...BRCA1 were functional in all HNSCCs, HPV+ cells showed downstream defects in both non-homologous end joining and homolog...

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