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PARP inhibitor maintenance therapy for patients with platinum-sensitive recur...

Smith(Haller J),Walters Haygood(Christen L... Gynecol Oncol 2016-01-07

...BRCA1/2 mutation and one for patients with wild-type BRCA1/2. Patients received six cycles of paclitaxel and carboplatin...

Moreton Lecture: Imaging in the Age of Precision Medicine.

Thrall(James H) J Am Coll Radiol 2016-07-11

...BRCA1 and BRCA2 genes. Imaging is poised to play major roles in the age of precision medicine. The imaging community nee...

Exome sequencing reveals frequent deleterious germline variants in cancer sus...

Ellingson(Marissa S),Hart(Steven N),Kalari... Breast Cancer Res Treat 2016-06-01

...BRCA1 (n = 4), BRCA2 (n = 8), CHEK2 (n = 2), FANCA (n = 1), FANCI (n = 1), FANCL (n = 1), FANCM (n = 1), FH (n = 1), MLH...

Prevalence of PALB2 mutations in Australian familial breast cancer cases and ...

Thompson(Ella R),Gorringe(Kylie L),Rowley(... Breast Cancer Res 2016-04-21

...BRCA1 and BRCA2. However, large studies that have evaluated the full gene rather than just the most common variants in b...

Clinical impact on ovarian cancer patients of massive parallel sequencing for...

Minucci(Angelo),Scambia(Giovanni),Santonoc... Expert Rev Mol Diagn 2016-06-13

...BRCA1/2 gene assay into routine clinical diagnostics. However, this study highlights the need of an integrated MPS BRCA1...

Serine/arginine-rich splicing factor 3 (SRSF3) regulates homologous recombina...

He(Xiaolong),Zhang(Pei) Mol Cancer 2016-05-17

...BRCA1, BRIP1 and RAD51, were enriched and were all downregulated. We demonstrated that the downregulation of BRCA1, BRIP...

SNP Set Association Testing for Survival Outcomes in the Presence of Intrafam...

Leclerc(Martin),,Simard(Jacques),Lakhal-Ch... Genet Epidemiol 2016-03-10

...BRCA1 and BRCA2.

A model for estimating ovarian cancer risk: application for preventive oophor...

Giannakeas(Vasily),Sopik(Victoria),Shestop... Gynecol Oncol 2016-02-08

...BRCA1/2 mutations.,Of the 6,301,340 women simulated as the general population of Ontario, the (complete) model predicts ...

High response rates to neoadjuvant platinum-based therapy in ovarian cancer p...

Gorodnova(Tatiana V),Sokolenko(Anna P),Iva... Cancer Lett 2016-03-16

...BRCA1 allele was detected only in 7/24 (29%) post-neoadjuvant therapy residual tumor tissues as compared to 9/11 (82%) B...

Breast cancer cells: Modulation by melatonin and the ubiquitin-proteasome sys...

Vriend(Jerry),Reiter(Russel J) Mol Cell Endocrinol 2016-10-05

...Brca1, functions as a ubiquitin ligase indicates that the ubiquitin-proteasome system has a role in regulating susceptib...

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