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Worse breast cancer prognosis of BRCA1/BRCA2 mutation carriers: what's the ev...

van den Broek(Alexandra J),Schmidt(Marjank... PLoS One 2016-03-15

...BRCA1 mutation carriers was found. For BRCA1 and BRCA2 there was a tendency towards a worse breast cancer-specific and o...

Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast c...

Downs(Bradley),Kim(Yeong C),Xiao(Fengxia),... Breast Cancer Res Treat 2016-01-25

...BRCA1+ and BRCA1x families. These studies show that mutations in PALB2 can occur independent of the status of BRCA1 muta...

Homologous recombination and human health: the roles of BRCA1, BRCA2, and ass...

Prakash(Rohit),Zhang(Yu),Feng(Weiran),Jasi... Cold Spring Harb Perspect Biol 2016-01-25

...BRCA1 and BRCA2, key players at different stages of HR, are frequently mutated in familial breast and ovarian cancers. O...

Massively Parallel Functional Analysis of BRCA1 RING Domain Variants.

Starita(Lea M),Young(David L),Islam(Muhtad... Genetics 2016-03-16

...BRCA1 variants to support homology-directed DNA repair, the essential role of BRCA1 in tumor suppression, and show that ...

The expression of DBC1/CCAR2 is associated with poor prognosis of ovarian car...

Cho(Dong),Park(Ho),Park(See-Hyoung),Kim(Ky... J Ovarian Res 2016-03-21

...BRCA1 and their prognostic significance in 104 ovarian carcinomas. Survival analyses were performed according to the Kap...

Genetically at-risk status and individual agency. A qualitative study on asym...

Caiata-Zufferey(Maria) Soc Sci Med 2016-01-12

...BRCA1/2 gene mutations. In the event of adverse results, women receive a specific label associated with a set of medical...

A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, co...

Jervis(Sarah),Song(Honglin),Lee(Andrew),Di... J Med Genet 2016-03-15

Although BRCA1 and BRCA2 mutations account for only ∼27% of the familial aggregation of ovarian cancer (OvC), no OvC ris...

Tumour characteristics and survival in familial breast cancer prospectively d...

Møller(Pål),Tharmaratnam(Kukatharmini),How... Breast Cancer Res Treat 2016-03-04

...BRCA1/2 mutation were subjected to annual mammography from age 30 years onwards. One-hundred and ninety-eight patients w...

BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer sy...

de Juan(Inmaculada),Palanca(Sarai),Domenec... Fam Cancer 2016-08-26

...BRCA1/BRCA2 mutational status in male relatives affected with cancer (MAC) and, family history and tumor types. The stud...

Biomarkers for efficacy of adjuvant chemotherapy following complete resection...

Wallerek(Sandra),Sørensen(Jens Benn) Eur Respir Rev 2016-03-09

...BRCA1, p53, MRP2, MSH2, TS, mucin, BAG-1, pERK1/2, pAkt-1, microRNA, TopIIA, 15-gene profile, 92-gene profile, 31-gene p...

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