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In vitro and in vivo correlates of physiological and neoplastic human Fallopi...

Yamamoto(Yusuke),Ning(Gang),Howitt(Brooke ... J Pathol 2016-08-10

...BRCA1 or BRCA2 mutations have documented a pre-metastatic intramucosal neoplasm that is found almost exclusively in the ...

miRNA expression patterns in normal breast tissue and invasive breast cancers...

Vos(Shoko),Vesuna(Farhad),Raman(Venu),van ... Oncotarget 2016-08-18

...BRCA1 and BRCA2 mutation carriers. miRNA profiles of 17 BRCA1- and 9 BRCA2-associated breast carcinomas were analyzed us...

The Angelina effect revisited: Exploring a media-related impact on public awa...

Lebo(Patricia Beatrice),Quehenberger(Franz... Cancer 2016-02-23

...BRCA1 positivity generated considerable media attention. To the authors' knowledge, the current study is the first prosp...

Large-scale genomic analyses link reproductive aging to hypothalamic signalin...

Day(Felix R),Ruth(Katherine S),Thompson(De... Nat Genet 2016-03-07

...BRCA1 associated with any complex trait. Mendelian randomization analyses supported a causal effect of later ANM on brea...

A BRCA1-interacting lncRNA regulates homologous recombination.

Sharma(Vivek),Khurana(Simran),Kubben(Nard)... EMBO Rep 2016-08-16

...BRCA1 and RAP80 at DSB sites. In line with a role in regulating HR, DDSR1 interacts with BRCA1 and hnRNPUL1, an RNA-bind...

Identification of germline genetic mutations in patients with pancreatic cancer.

Salo-Mullen(Erin E),O'Reilly(Eileen M),Kel... Cancer 2016-04-04

...BRCA1 (4 mutations), p16 (2 mutations), PALB2 (1 mutation), and Lynch syndrome (4 mutations). BRCA1/BRCA2 prevalence was...

Targeting tumor suppressor genes for cancer therapy.

Liu(Yunhua),Hu(Xiaoxiao),Han(Cecil),Wang(L... Bioessays 2016-11-02

...BRCA1/2. Here, we review and summarize the recent findings in cancer genomics, drug development, and molecular cancer bi...

BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, ...

Sakamoto(Ikuko),Hirotsu(Yosuke),Nakagomi(H... Cancer 2016-06-06

...BRCA1 and BRCA2. Notably, 6 of the 59 cases (10.2%) without a family history also had BRCA1/2 germline mutations. There ...

Molecular signature of pancreatic adenocarcinoma: an insight from genotype to...

Sahin(Ibrahim H),Iacobuzio-Donahue(Christi... Expert Opin Ther Targets 2016-09-29

...BRCA1 and BRCA2 genes and their role in pancreatic cancer treatment are elaborated upon. We further review recent genomi...

The History of Patenting Genetic Material.

Sherkow(Jacob S),Greely(Henry T) Annu Rev Genet 2016-09-19

...BRCA1 and BRCA2, two genes critical to assessing early-onset breast and ovarian cancer risk, and with a particularly con...

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