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Quantitative detection of methylation of FHIT and BRCA1 promoters in the seru...

Liu(Limei),Sun(Liyuan),Li(Chunhe),Li(Xinya... Biomed Mater Eng 2016-07-22

...BRCA1 promoters using the bisulphite sequencing method (BSP) and high-resolution melting curve analysis (HRM) in the ser...

RAD51C mutation screening in high-risk patients from Serbian hereditary breas...

Krivokuca(Ana),Yanowski(Kira),Rakobradovic... Cancer Biomark 2016-10-18

...BRCA1/2 genes. Whole coding region and exon-intron boundaries of RAD51C were analyzed by dHPLC. All mutations were confi...

Targeted Sequencing of the Mitochondrial Genome of Women at High Risk of Brea...

Blein(Sophie),Barjhoux(Laure),,Damiola(Fra... PLoS One 2016-05-27

...BRCA1/2 pathogenic mutations. We sequenced the mitochondrial genome of 436 index breast cancer cases from the GENESIS st...

Biomarkers in Breast Cancer: Where Are We and Where Are We Going?

Duffy(Michael J),Walsh(Siun),McDermott(End... Adv Clin Chem 2016-04-15

...BRCA1/2 mutation testing is used for risk assessment in families with a high prevalence of breast and ovarian cancer. Fo...

Tools for translational epigenetic studies involving formalin-fixed paraffin-...

Wong(Ee Ming),Joo(JiHoon E),McLean(Catrion... BMC Res Notes 2016-06-30

...BRCA1 promoter region showed increased methylation in triple-negative breast cancers compared to Luminal A, Luminal B an...

Uptake of risk-reducing salpingo-oophorectomy among female BRCA mutation carr...

Kim(Se Ik),Lim(Myong Cheol),Lee(Dong Ock),... J Cancer Res Clin Oncol 2016-05-17

...BRCA1 or BRCA2 mutation carriers at the National Cancer Center of Korea.,Between April 2007 and December 2014, 450 women...

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Ind...

Castella(Maria),Jacquemont(Celine),Thompso... PLoS Genet 2016-04-29

...BRCA1 was required for efficient FA core complex foci formation. These findings indicate that FANCI functions upstream o...

BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, ...

Sakamoto(Ikuko),Hirotsu(Yosuke),Nakagomi(H... Cancer 2016-06-06

...BRCA1 and BRCA2. Notably, 6 of the 59 cases (10.2%) without a family history also had BRCA1/2 germline mutations. There ...

Molecular signature of pancreatic adenocarcinoma: an insight from genotype to...

Sahin(Ibrahim H),Iacobuzio-Donahue(Christi... Expert Opin Ther Targets 2016-09-29

...BRCA1 and BRCA2 genes and their role in pancreatic cancer treatment are elaborated upon. We further review recent genomi...

Optimal surgical management for high-risk populations.

King(Tari A),Pilewskie(Melissa),Morrow(Mon... Breast 2016-08-23

...BRCA1 or BRCA2 are frequently considered to be at highest risk of local failure, leading to speculation that more-aggres...

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