...BRCA1/2 genes. Whole coding region and exon-intron boundaries of RAD51C were analyzed by dHPLC. All mutations were confi...
...BRCA1/2 pathogenic mutations. We sequenced the mitochondrial genome of 436 index breast cancer cases from the GENESIS st...
...BRCA1/2 mutation testing is used for risk assessment in families with a high prevalence of breast and ovarian cancer. Fo...
...BRCA1, in a manner independent of its E3 ligase activity but depending on E2F1, a well-known transcription factor of BRC...
...BRCA1-Associated Protein 1 (BAP1) germline mutations, with high incidence of mesothelioma, uveal melanoma and other canc...
In Brazil, several recurring mutations in BRCA1 and BRCA2 and a TP53 mutation (R337H) have been reported in high risk br...
BRCA1 associated protein 1 (BAP1) is a nuclear deubiquitinase that regulates tumor suppressor activity and widely involv...
...BRCA1 gene, as well as overexpression of oncogenic kinases, such as human epidermal growth factor receptor 2, vascular e...
...BRCA1/ 2 mutation carriers, an update of these guidelines is urgently needed. Another reason is a higher incidence of ot...
Population with hereditary breast and ovarian cancer syndrome, i.e. BRCA1/2 mutation carriers, are at higher risk of dev...
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