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DREAMing: a simple and ultrasensitive method for assessing intratumor epigene...

Pisanic(Thomas R),Athamanolap(Pornpat),Poh... Nucleic Acids Res 2016-06-21

...BRCA1 gene-promoter loci in liquid biopsies obtained from patients in association with non-small cell lung cancer (NSCLC...

Analysis of PALB2 in a cohort of Italian breast cancer patients: identificati...

Vietri(Maria Teresa),Caliendo(Gemma),Schia... Fam Cancer 2016-06-10

...BRCA1 and BRCA2 (BRCAX). Genomic DNA was isolated from peripheral blood lymphocytes, PALB2 coding regions and adjacent i...

Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif.

Wu(Qian),Jubb(Harry),Blundell(Tom L) Prog Biophys Mol Biol 2016-02-03

BRCA1 BRCT domains function as phosphoprotein-binding modules for recognition of the phosphorylated protein-sequence mot...

Reconstruction of canine diffuse large B-cell lymphoma gene regulatory networ...

Zamani-Ahmadmahmudi(M),Najafi(A),Nassiri(S M) J Comp Pathol 2016-01-13

...BRCA1, MYCN, RFC4 and POLA1 as the most important hub genes. The phosphatidyl inositol signalling system, P53 signalling...

Large genomic rearrangements in the familial breast and ovarian cancer gene B...

James(Paul A),Sawyer(Sarah),Boyle(Samantha... Fam Cancer 2016-03-08

...BRCA1 LGR the mean age of breast cancer diagnosis was younger than in families with a non-LGR BRCA1 mutation (42.5 vs. 4...

The role of the prostate cancer gene 3 urine test in addition to serum prosta...

Cremers(Ruben G),Eeles(Rosalind A),Bancrof... Urol Oncol 2016-03-02

...BRCA1 mutation carriers, 75 BRCA2 mutation carriers, and 308 noncarriers. The physicians and participants were blinded f...

Dysregulation of X chromosome inactivation in high grade ovarian serous adeno...

Kang(Jun),Lee(Hee Jin),Kim(Jiyoung),Lee(Ja... PLoS One 2016-02-02

...BRCA1 mutation-associated breast cancers. We investigated the clinical implications of the loss of XCI in ovarian cancer...

Ancestry dependent DNA methylation and influence of maternal nutrition.

Mozhui(Khyobeni),Smith(Alicia K),Tylavsky(... PLoS One 2016-02-02

...BRCA1, MCC). Overall, there is lower global methylation in African ancestral groups. Plasma levels of 25-hydroxy vitamin...

Heterozygous germline mutations in NBS1 among Korean patients with high-risk ...

Kim(Haeyoung),Cho(Dae-Yeon),Choi(Doo Ho),J... Fam Cancer 2016-06-10

...BRCA1/2 mutation. We screened 235 non-BRCA1/2 Korean patients with high-risk breast cancer for NBS1 mutations. The entir...

Effect of BRCA1 and XPG mutations on treatment response to trabectedin and pe...

Monk(B J),Ghatage(P),Parekh(T),Henitz(E),K... Ann Oncol 2016-05-19

...BRCA1(mut) patients (20/41; 49%) versus BRCA1(wt) patients (62/223; 28%). Within the BRCA1(mut) group, trabectedin + PLD...

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