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TP53 BRCA1 CRISPR single-cell cancer

Moiseyenko(Vladimir M),Dolmatov(Georgiy D)... Med Oncol 2016-03-15

...BRCA1 germ-line mutation carriers usually involves somatic inactivation of the remaining BRCA1 allele. This feature lead...

Tangutoori(Shifalika),Baldwin(Paige),Sridh... Maturitas 2016-03-31

...BRCA1 or BRCA2 mutations. Currently, clinical trials with several PARP inhibitors are being conducted to assess the toxi...

Nelson(Brad H) Curr Opin Immunol 2016-01-01

...BRCA1 disruption; the latter may promote immunity through altered cytokine signaling, oxidative stress responses, or ant...

Wevers(M R),Schmidt(M K),Engelhardt(E G),V... Fam Cancer 2016-06-10

...BRCA1/2 carrier status before primary surgery. Considering the potential impact of knowing one's status on uptake and ti...

Walsh(E M),Farrell(M P),Nolan(C),Gallagher... Ir J Med Sci 2016-08-25

...BRCA1/2 mutation carriers with clinical breast exam, mammography and MRI has reported sensitivity of 100 %, but BRCA1/2 ...

Pettapiece-Phillips(Rachael),Narod(Steven ... Cancer Causes Control 2016-03-29

...BRCA1 or BRCA2 gene and thereby normalize protein levels, contribute to stem cell homeostasis, and/or affect hormone lev...

Knopf(Andreas),Lempart(Justine),Bas(Murat)... Oncotarget 2016-03-28

...BRCA1, E2F1, FHIT, RUNX3, STK11, BCL2, CTNNB1).,The median overall survival was 142 (≤45 years) and 34 months (>45 years...

Wu(Wenwen),Nishikawa(Hiroyuki),Fukuda(Taka... Cancer Res 2016-01-23

Stable retention of BRCA1/BARD1 complexes at sites of DNA damage is required for the proper response to DNA double-stran...

Rosenthal(E T),Bowles(K R),Pruss(D),van Ka... Clin Genet 2016-08-31

...BRCA1, BRCA2 and MSH2 that are predicted to disrupt splicing, prematurely truncate the protein, or remove the start codo...

Trujillano(Daniel),Weiss(Maximilian E R),S... J Mol Diagn 2016-04-25

...BRCA1 and BRCA2 mutations and polymorphisms. Genomic DNA was amplified using the Ion AmpliSeq BRCA1 and BRCA2 panel. The...

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