...MSH2, MSH6 and PMS2, (2) aiding MMR gene variant interpretation and (3) deciding on use of immune checkpoint blockade th...
...MSH2, and MSH6) was assessed to evaluate MSI status. Gonadotroph tumors were the most common subtype (45.5%). Statistica...
...MSH2 expression was lost in the high-grade adenocarcinoma component, but retained in the adenomatous and low-grade adeno...
...Msh2 with doxycycline-inducible expression of the proofreading-deficient PolεP286R mutant in murine small cell lung canc...
...MSH2 when the recombining sequences contain mismatches. Given the repetitive nature of our genome, these findings highli...
...MSH2, and TP53, which may contribute to tumorigenesis and progression. Despite therapeutic efforts, both patients died w...
...MSH2, MSH6, PMS2) and other variants (ATM, CDKN2A, FLCN, MITF, POT1, PTEN, TP53) at the HCC at the Medical University of...
...MSH2, MSH6, and PMS2. Population-specific variant frequencies emphasize the need for localized genetic studies. Methods ...
...MSH2/MSH6 loss in 12, and complete loss of all MMR proteins in two tumors. The distribution of MMR deficiency varied by ...
...MSH2) is thought to be the primary event in the expansion process. This starts a cascade that leads to error-prone repai...
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