...BRCA1-deficient cells showing that DSB mobility can be detrimental in cells with numerous DSBs. In contrast, under physi...
...BRCA1, CD44, ESR1, GSTM2, GSTP1, MAGEA1, MSI1, NFE2L3, RASSF1A, RUNX3, SIX3 and TFF1), far-upstream regions (EN1, PAX3, ...
Impairment of homologous recombination (HR) is found in close to 50 % of ovarian and breast cancer. Tumors with BRCA1 mu...
...BRCA1/2 mutation, family history) focus on reducing estrogen exposure. Women at elevated risk may be interested in less ...
...BRCA1/2 status and in 1,012 controls from Pakistan. The association between SNP genotypes and breast cancer risk was inv...
...BRCA1 interacts with BARD1 to constitute a RING heterodimer-type E3 ubiquitin ligase. BRCA1-associated protein 1 (BAP1) ...
...BRCA1 mutated breast cancers.,We performed high-resolution SNP array and gene expression profiling of 120 familial breas...
...BRCA1 mutations and 68 (4.8%) had BRCA2 mutations. A status of no residual disease was achieved by 39% of non-carriers a...
...BRCA1 and cyclin D1, and cell death is triggered following reductions of MYC and nucleolin and an accumulation of apopto...
Germline mutations in the BRCA1 and BRCA2 genes account for 20-25 % of inherited breast cancers and about 10 % of all br...
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