...BRCA1 expression detected in 60-65%. A potential link between BRCA1 expression and overall survival (M stage adjusted) i...
...BRCA1 and BRCA2.,In 13 (12 %) patients a deleterious mutation in BRCA1/2 was detected, three of which were novel mutatio...
...BRCA1, BRCA2, BARD1, ATM, RAD51 and NBS1 in EOC cell lines and paraffin-embedded tissue sections from 140 EOC patients t...
...BRCA1 (3 subjects; 6%), BRCA2 (2 subjects; 4%), TP53 (tumor protein p53) (3 subjects; 6%), CHEK2 (checkpoint kinase 2) (...
...BRCA1 C-terminal (BRCT) domains, which typically recognize phospho-peptides. Thus Rtt107 represented an opportunity to s...
...BRCA1-like or non-BRCA1-like identified patients enriched for defects in BRCA1 that benefit from high-dose (HD) alkylati...
...BRCA1 carriers and 1.6 times and 2.4 times, respectively, for BRCA2 carriers.,Mutation carriers, particularly BRCA1 carr...
...BRCA1/BRCA2 testing in Ashkenazi Jews is supported by data that demonstrate population-based BRCA1/BRCA2 testing does no...
...BRCA1 protein expression. In conclusion, this study indicated that BRCA1 promoter methylation appeared to be a useful pr...
...BRCA1 or BRCA2 gene mutations (40% and 18% risk, respectively, by age 70 years) or hereditary nonpolyposis colorectal ca...
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