文献库搜索 | GeneLibs

Lebeau(A),Schmutzler(R) Pathologie (Heidelb) 2026-09-00

Approximately 5-10% of all breast cancers arise from a hereditary predisposition. In addition to the high-risk genes BRC...

Banda(K),Davies(HR),Kumar(Y),Memari(Y),Deg... Clin Cancer Res 2026-05-27

...BRCA1/2 mutations or BRCA1 promoter methylation, while 22.1% lacked BRCA1/2 alterations. A substantial fraction (23.2%) ...

Wang(J),Li(X),Chang(J),Hou(X),Yan(Y),Chen(... 3 Biotech 2026-06-00

...BRCA1 expression by reducing methylation of the BRCA1 promoter. Furthermore, USP39 knockdown sensitized resistant cells ...

Sturm(AC),Detweiler(S),Bielenberg(J),Park(... Genet Med Open None

...BRCA1, BRCA2, APOB, LDLR, HFE, TTR, or MUTYH and had opened their report. Main outcomes included personal and family his...

Živić(K),Boljević(I),Matović(M),Nedeljkovi... JCO Precis Oncol 2026-05-00

...BRCA1/2 genes from tumor tissue is currently recommended as a companion diagnostic procedure for selection of patients e...

Bernini(M),Innocenti(S),Turchetti(D),Micco... World J Surg Oncol 2026-05-28

...BRCA1 and 89 BRCA2 carriers), 22.5% elected to undergo BRRM, with a significantly higher uptake among BRCA1 carriers (33...

Valencia Nieto(P),García Álvarez(C),García... Front Oncol None

...BRCA1-associated protein 1 (BAP1) nuclear expression in enucleated eyes with uveal melanoma (UM), and to compare its pre...

Schreuder(A),de Lint(K),Mỹ Phúc Võ(H),Góis... Mol Oncol 2026-05-29

...BRCA1 missense mutations and compare these to a BRCA1-depleted setting to study whether this affects screening for synth...

Törnblom(A),He(C),Bolin(M),Tzortzakakis(A)... EJNMMI Res 2026-08-19

...BRCA1/2 mutations. However, not all patients respond to these drugs, and therapy-predictive biomarkers are needed to opt...

Alzate(D),Sánchez(AY),Pacheco(Y),Isaza Rug... PLoS One None

...BRCA1. These genes are involved in the molecular pathway of DNA repair by homologous recombination (HRD). Our results de...