...SLX4. At the present time, little is known about the structure of SLX1-SLX4 or its mechanism of action. Here, we report ...
SLX4 is a multidomain platform that regulates various proteins that are involved in genome maintenance and stability. Am...
The SLX1-SLX4 complex is a structure-specific endonuclease that cleaves branched DNA structures and plays significant ro...
...SLX4) complex and to promote cell cycle arrest. Vpr also interferes with the base-excision repair pathway by antagonizin...
...SLX4 acts as a scaffold for building this complex, the molecular basis underlying this function of SLX4 remains unclear....
...SLX4 genes, both located on chromosome 16, were the affected recessive FA genes in three and one family respectively. Ge...
...Slx4 protein plays key roles in the processing of recombination intermediates, functioning as a scaffold to coordinate t...
...Slx4 has been believed to play only a minor role in meiotic recombination. Here, we report that Slx4 is involved in prop...
...SLX4, MUS81 and GEN1, involved in the resolution of HJ. Altogether, our results suggest that the telomere maintenance me...
...SLX4(FANCP) deficiency as a working model, we questioned the trigger for chronic inflammation in FA. We found that absen...
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