...BRCA1/2 alterations, confirming a clonal association between these lesions. Next-generation sequencing confirmed the pre...
...BRCA1 or BRCA2 mutation, surgical stage, residual tumor, and patient age, ADAMTS mutations were significantly associated...
...BRCA1/2) mutations, have elevated hopes of a bright future in the biomarker-driven therapeutic arena.,As the clinical ap...
...BRCA1-like or non-BRCA1-like identified patients enriched for defects in BRCA1 that benefit from high-dose (HD) alkylati...
In Brazil, several recurring mutations in BRCA1 and BRCA2 and a TP53 mutation (R337H) have been reported in high risk br...
...BRCA1 carriers and 1.6 times and 2.4 times, respectively, for BRCA2 carriers.,Mutation carriers, particularly BRCA1 carr...
...BRCA1/2 variant) and from controls. We used the support vector machines algorithm to differentiate between patients who ...
...BRCA1 or BRCA2 gene mutations (40% and 18% risk, respectively, by age 70 years) or hereditary nonpolyposis colorectal ca...
...BRCA1, BRCA2, ERBB2 and CCNE1 copy number changes in DNA extracted from snap-frozen and FFPE tumour tissue, with 100% se...
...BRCA1 (3 subjects; 6%), BRCA2 (2 subjects; 4%), TP53 (tumor protein p53) (3 subjects; 6%), CHEK2 (checkpoint kinase 2) (...
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