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TP53 BRCA1 CRISPR single-cell cancer

Szatkowski(Wiktor),Blecharz(Paweł),Mituś(J... Hered Cancer Clin Pract 2016-01-25

...BRCA1-dependent OC (BRCA1-OC).,The records of patients with OC treated with surgery and chemotherapy at the Centre of On...

Nair(Sreejith J),Zhang(Xiaowen),Chiang(Hua... Nat Commun 2016-07-20

...BRCA1 is well known for its function in double-strand break (DSB) DNA repair. While BRCA1 is also implicated in transcri...

Prog Drug Res 2016-04-08

...BRCA1 or BRCA2 genes and COX proteins is carefully texted in this chapter to check docking of the best inhibitor molecul...

Silvestri(Valentina),Barrowdale(Daniel),Mu... Breast Cancer Res 2016-10-05

...BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers ...

Robinson(Linda S),Hendrix(Ashley),Xie(Xian... EBioMedicine 2016-11-04

...BRCA1/2 mutation carriers.,We identified 20 of the 85 (23.5%) expected BRCA1/2 mutation carriers in the underserved popu...

Phi(Xuan-Anh),Saadatmand(Sepideh),De Bock(... Br J Cancer 2016-07-20

...BRCA1/2 mutation carriers of all ages (BRCA1 = 1,219 and BRCA2 = 732), adding mammography to MRI did not significantly i...

Menkiszak(Janusz),Chudecka-Głaz(Anita),Gro... J Ovarian Res 2016-10-11

...BRCA1/BRCA2 carriers.,One hundred ninety-five patients, carriers of one of three most common mutations of the BRCA1 gene...

Yasukawa(Masaaki),Fujihara(Hisako),Fujimor... Int J Mol Sci 2016-11-04

...BRCA1/2 mutated breast and ovarian cancers, or certain solid cancers in combination with anti-cancer drugs. However, the...

Thompson(Ella R),Rowley(Simone M),Li(Na),M... J Clin Oncol 2016-11-10

...BRCA1 and BRCA2 wild type. Controls (n = 1,997) were cancer-free women from the LifePool study. Sequencing data were fil...

Hong(Ye),Sonneville(Remi),Agostinho(Ana),M... PLoS Genet 2016-08-09

...BRCA1 ortholog BRC-1. Furthermore, the combined deletion of smc-5 and him-6 leads to an irregular distribution of conden...

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