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Tumor suppressor genes and their underlying interactions in paclitaxel resist...

Xu(Jia-Hui),Hu(Shi-Lian),Shen(Guo-Dong),Sh... Cancer Cell Int 2016-02-22

...BRCA1, TP53, PTEN, APC, CDKN1A, CDKN2A, HIN-1, RASSF1, YAP, ING4, PLK2, FBW7, BLU, LZTS1, REST, FADD, PDCD4, TGFBI, ING1...

Recurrent mutations of BRCA1, BRCA2 and PALB2 in the population of breast and...

Wojcik(P),Jasiowka(M),Strycharz(E),Sobol(M... Hered Cancer Clin Pract 2016-02-04

...BRCA1 accounted for 91 % of all BRCA1 mutation carriers (c.5266dupC was identified in six patients and c.181 T > G was i...

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination ...

Trego(Kelly S),Groesser(Torsten),Davalos(A... Mol Cell 2016-07-26

...BRCA1. Its depletion causes BRCA1 hyper-phosphorylation and persistent chromatin binding. These unexpected findings esta...

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes i...

Cao(Wen-Ming),Gao(Yun),Yang(Hong-Jian),Xie... BMC Cancer 2016-09-29

...BRCA1 and BRCA2 were screened by PCR-sequencing assay. Haplotype analysis was performed to confirm BRCA1 and BRCA2 found...

Tracking of the origin of recurrent mutations of the BRCA1 and BRCA2 genes in...

Cini(Giulia),Mezzavilla(Massimo),Della Pup... BMC Med Genet 2016-05-11

...BRCA1 and BRCA2 genes. Since BRCA1 and BRCA2 mutations may be spread throughout the gene, genetic testing is usually per...

[Hormonotherapy for breast cancer prevention: What about women with genetic p...

Sénéchal(Claire),Reyal(Fabien),Callet(Nasr... Bull Cancer 2016-07-18

In France, women carrying BRCA1/2 mutation, at an identified high risk of breast cancer are recommended to undergo breas...

Twenty-one-gene recurrence score assay in BRCA-associated versus sporadic bre...

Shah(Payal D),Patil(Sujata),Dickler(Maura ... Cancer 2016-08-22

...BRCA1/BRCA2 carriers (cases) were identified and matched (1:2) by age at diagnosis and tumor size to noncarrier controls...

Genomic characterization of sarcomatoid transformation in clear cell renal ce...

Bi(Mark),Zhao(Siming),Said(Jonathan W),Mer... Proc Natl Acad Sci U S A 2016-07-25

...BRCA1 associated protein 1 (BAP1) were significantly mutated in sarcomatoid elements and were mutually exclusive with TP...

MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts.

Aparicio(Tomas),Baer(Richard),Gottesman(Ma... J Cell Biol 2016-08-01

...BRCA1 are required for both the removal of Top2-DNA adducts and the subsequent resection of Top2-adducted DSB ends. More...

Chromosomal microarray provides enhanced targetable gene aberration detection...

Mukherjee(S),Ma(Z),Wheeler(S),Sathanoori(M... Cancer Genet 2016-09-22

...BRCA1 and NF1 among male patients with lung cancer. For clinically actionable targets, 23% had targetable CNVs when no p...

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