...BRCA1/2 mutation carriers.,We identified 20 of the 85 (23.5%) expected BRCA1/2 mutation carriers in the underserved popu...
...BRCA1 in mitosis. Aurora-A, in turn, then phosphorylates BRCA1 itself, thereby inhibiting the mitotic function of BRCA1 ...
...BRCA1-associated protein 1 (BAP1) gene alterations that are associated with high tumor grade and poor prognosis. We hypo...
...BRCA1-associated protein 1 (BAP1) dysfunction compatible with diffuse malignant peritoneal mesothelioma (DMPM).,We descr...
...BRCA1&2, ATRX and KMT2D mutations have roles in the development of PCC/PGLs. Overall, known genetic mutations account fo...
...BRCA1 mutation show similar histologic features and a triple-negative phenotype. Not all TNBCs are associated with an un...
...BRCA1) or its down-regulation are involved in its development. Down-regulation of BRCA1 expression by hypermethylation o...
...BRCA1/2-mutation carriers that could potentially benefit from the synthetic lethality of PARP inhibitors. This integrate...
...BRCA1 expression in other cancers.,To evaluate the expression of these microRNAs in relation to BRCA1 expression in TNBC...
...BRCA1 or BRCA2 genes. The majority of BRCA1 and BRCA2 cancers are high-grade serous carcinomas diagnosed at an advanced ...
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