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HRR gene promoter methylation-guided nomogram predicts PARP inhibitor efficac...

Zhou(Z),Ge(B),Chen(T),Shen(S),Tu(N),Shen(Y... Clin Epigenetics 2026-05-19

...BRCA1(2S)_Pos2, BRCA2(1S)_Pos1, BRCA2(1S)_Pos7, and RAD51D_Pos6-were identified as independent predictors of PARPi sensi...

Triple-negative breast cancer: current understanding and future perspectives.

Alobaidi(A),Rai(V) Explor Target Antitumor The... None

...BRCA1 mutation carriers. Standard management typically involves neoadjuvant chemotherapy followed by surgery and potenti...

Lower expression of BRCA1 in cardiomyoblast alters the expression of apoptoti...

Tariq(U),Sarkar(S),Kumar(R),Chakraborty(S)... Gene 2026-10-10

...BRCA1-knockdown H9c2 cells. Successful knockdown of BRCA1 was achieved by developing lentiviral particles containing BRC...

Contralateral breast cancer risks for BRCA1, BRCA2, PALB2, CHEK2, and ATM pat...

Allen(I),Whish(N),Yadav(S),Boddicker(NJ),D... BJC Rep 2026-06-03

...BRCA1/2 and CHEK2 PV carriers following ER-positive BC, and in BRCA1/2 and PALB2 PV carriers following ER- negative BC. ...

Vacuolar sorting receptors regulates autophagic trafficking of pathogenic eff...

Hu(S),Zhu(D),Gao(Y),Rojo(E),Shen(J) Autophagy 2026-06-09

...BRCA1 gene 1 protein; FLS2, FLAGELLIN-SENSING 2.

Clinical Performance of International and Korean Genetic Testing Criteria for...

Lee(BY),Lee(HJ),Kim(J),Kim(D),Jeong(J),Yoh... J Breast Cancer 2026-06-00

...BRCA1/2 sequencing, multiplex ligation-dependent probe amplification, and multigene panels. Eligibility was determined a...

Impact of Germline BRCA1/2 Mutations on Clinical Outcomes in Metastatic Tripl...

Pacholczak-Madej(R),Püsküllüoğlu(M),Polaki... Oncol Res None

...BRCA1/2 mutations (gBRCA1/2m) and those with gBRCA1/2 wild-type (gBRCA1/2wt) using Kaplan-Meier estimates, the log-rank ...

Disrupted STIL-BRCA1 axis causes centrosome amplification and genomic instabi...

Sanghi(S),Joshi(M),Singh(P) FEBS Lett 2026-07-00

...BRCA1, thereby destabilizing BRCA1 and leading to centrosome amplification and DNA damage.

Genetically Shared Signatures Between COVID-19 and Cancer Identified Through ...

Ahmed(AYA),Akçay(S) Genes (Basel) 2026-01-28

...BRCA1, and TP53, modulated both viral and oncogenic processes. Severe COVID-19 was associated with enhanced inflammatory...

Semi-Quantitative Evaluation of BRCA1 Protein in Breast Tumors Using Anti-BRC...

Anton(SC),Nedelcu(AH),Ianole(V),Anton(C),D... Int J Mol Sci 2026-02-11

...BRCA1 germline mutation carriers, present significant clinical challenges. The role of BRCA1 protein expression, assesse...

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