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Pathological features and prognosis based on microsatellite stability status in…

Liu(X),Yang(Y),Zheng(H),Zhang(Y) Int J Clin Exp Pathol None

...MSH2), MutS homolog 6 (MSH6), and PMS1 homolog 2 (PMS2), in CRC and normal tissues using the Tumor, Normal and Metastati...

Intramuscular patient-derived xenografts achieve high engraftment rates in gast…

Li(B),Wang(B),Song(H),Zheng(H),Wang(Q),Deng(… Ann Med 2026-12-00

...MSH2 predominated in fast-growing grafts, whereas TP53, CHD3 and TET2 were enriched in slow-growing grafts. Slow-growing...

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates R…

Odintsov(I),Nowak(JA),Baranov(E),Alcindor(T)… Am J Surg Pathol 2026-09-01

...MSH2 , 9 MLH1 , 4 PMS2 , 4 MSH6 , 1 EPCAM ). All tumors evaluated with immunohistochemistry (IHC; n = 36) showed loss of...

KRAS/NRAS/BRAF Mutations and Mismatch Repair Deficiency in Patients with Early-…

Liu(C),Wang(Y) Int J Surg Pathol 2026-06-12

...MSH2, MSH6) expression was evaluated by immunohistochemistry. Pearson's chi-squared test was used to assess the relation...

Phenotypic heterogeneity in carriers of a pathogenic MSH2 variant: implications…

Apuhan(T),Demir(O),Sagnak Yilmaz(Z),Karaman(… J Cancer Res Clin Oncol 2026-06-13

...MSH2 variant may exhibit heterogeneous tumor-level MMR/MSI phenotypes. Early truncating variants in MSH2 may allow parti...

Case Report: Converting an immunologically "cold" tumor: exceptional response t…

Ni(C),Xu(J),Pang(Y),Xu(J) Front Immunol None

...MSH2, MSH6, PMS2) and confirmed by next-generation sequencing (NGS). Following disease progression on first-line gemcita...

Cytological Diagnosis of Primary Cardiac Angiosarcoma Presenting With Multiple …

Xu(C),Gong(Y) Diagn Cytopathol 2026-09-00

...MSH2 (c.14C>A, p.Pro5Gln) with a variant allele frequency (VAF) of 48%, confirming the feasibility of CB as an alternati...

Case of complete response to immunotherapy in MMR-deficient prostate cancer ass…

Tsai(AK),Lozada(JR),Kennedy(PR),Moline(D),Pa… Cell Rep Med 2026-07-21

...MSH2 and MSH6 genomic deletions with ultrahigh TMB (>250 mutations/megabase) in whom pembrolizumab resulted in a strikin...

Relationship between MLH1, MSH2, MSH6, and PMS2 protein expression status and c…

Hu(W),Hu(X),Xie(E),Wang(Y) Front Med (Lausanne) None

...MSH2, MSH6, and PMS2). Patients were classified as dMMR or pMMR. Associations between MMR status and various clinicopath...

Cholangiocarcinoma with metachronous urothelial malignancy as a rare manifestat…

Joel(S),Shah(S) BMJ Case Rep 2026-06-29

...MSH2/MSH6, hence confirming the diagnosis of Lynch syndrome. This enabled the decision to treat with immunotherapy for r...

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