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Clinicopathological values of NBS1 and DNA damage response genes in epithelia...

Lee(Yoo-Kyung),Park(Noh-Hyun),Lee(Hyunsook... Exp Mol Med 2016-08-11

...BRCA1, BRCA2, BARD1, ATM, RAD51 and NBS1 in EOC cell lines and paraffin-embedded tissue sections from 140 EOC patients t...

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ova...

Meeks(Huong D),Song(Honglin),Michailidou(K... J Natl Cancer Inst 2016-03-14

...BRCA1 variant carriers. All statistical tests were two-sided.,The K3326X variant was associated with breast (ORw = 1.28,...

Comparison of impedimetric detection of DNA hybridization on the various bios...

Benvidi(Ali),Tezerjani(Marzieh Dehghan),Ja... Talanta 2016-09-12

...BRCA1 5382insC mutation using independent glassy carbon electrodes (GCE) modified with RGO and MWCNTs. A probe (BRCA1 53...

Targeting the DNA Damage Response in Cancer.

O'Connor(Mark J) Mol Cell 2016-03-09

...BRCA1 or BRCA2 mutations, represents the first medicine based on this principle, exploiting an underlying cause of tumor...

Nanoscopic exclusion between Rad51 and 53BP1 after ion irradiation in human H...

Reindl(Judith),Drexler(Guido A),Girst(Stef... Phys Biol 2016-07-08

...Brca1, CtIP and RPA. Furthermore, localization relative to 53BP1 and size of Rad51 foci was not different after irradiat...

DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cogn...

Suberbielle(Elsa),Djukic(Biljana),Evans(Ma... Nat Commun 2016-06-29

...BRCA1 levels in primary neuronal cultures. In wild-type mice, knocking down neuronal BRCA1 in the dentate gyrus caused i...

Breast Cancer Risk Assessment: Moving Beyond BRCA 1 and 2.

Scalia-Wilbur(Jennifer),Colins(Bradley L),... Semin Radiat Oncol 2016-09-19

...BRCA1 and BRCA2 are available. However, the indications for both screening and prevention of inherited predispositions b...

Centrosomes in the DNA damage response--the hub outside the centre.

Mullee(Lisa I),Morrison(Ciaran G) Chromosome Res 2016-10-17

...BRCA1 ubiquitin ligase complex and several members of the poly(ADP-ribose) polymerase family. Stereotypical centrosome o...

Ten-year survival after epithelial ovarian cancer is not associated with BRCA...

Kotsopoulos(Joanne),Rosen(Barry),Fan(Isabe... Gynecol Oncol 2016-04-28

...BRCA1 mutations and 68 (4.8%) had BRCA2 mutations. A status of no residual disease was achieved by 39% of non-carriers a...

The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via D...

Kaufman(Kimberley L),Jenkins(Yiping),Aloma... Oncotarget 2016-09-28

...BRCA1 and cyclin D1, and cell death is triggered following reductions of MYC and nucleolin and an accumulation of apopto...

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