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TP53 BRCA1 CRISPR single-cell cancer

Nomura(Hiroyuki),Kataoka(Fumio),Aoki(Daisu... Cancer Biomark 2016-11-04

...BRCA1 expression detected in 60-65%. A potential link between BRCA1 expression and overall survival (M stage adjusted) i...

Francies(F Z),Wainstein(T),De Leeneer(K),C... BMC Cancer 2016-06-29

...BRCA1 and BRCA2.,In 13 (12 %) patients a deleterious mutation in BRCA1/2 was detected, three of which were novel mutatio...

Hussein(Yaser R),Ducie(Jennifer A),Arnold(... Am J Surg Pathol 2016-06-29

...BRCA1 or BRCA2 germline mutation retrieved from our institutional files, 23 patients had a germline mutation of BRCA1 an...

Mace(Thomas A),Shakya(Reena),Elnaggar(Omar... Oncotarget 2016-10-31

...Brca1 alleles (KPC-Brca1 mice). Mice with confirmed tumor burden were treated orally with vehicle or 30 mg/kg BMS-911543...

Ma(Yongxian),Preet(Anju),Tomita(York),De O... Oncotarget 2016-10-05

...BRCA1 protein binds to estrogen receptor-alpha (ER) and inhibits its activity. Here, we found that BRCA1 over-expression...

Nakamura(Seigo),Kwong(Ava),Kim(Sung-Won),I... Public Health Genomics 2016-08-19

BRCA1/BRCA2 mutations are associated with an increased lifetime risk for hereditary breast and ovarian cancer (HBOC). Co...

Damiola(Francesca),Schultz(Inès),Barjhoux(... Breast Cancer Res Treat 2016-09-06

...BRCA1 and BRCA2 pathogenic mutations. Our analysis revealed the presence of four novel deleterious mutations: c.1186insT...

Dutil(Julie),Golubeva(Volha A),Pacheco-Tor... Breast Cancer Res Treat 2016-09-06

...BRCA1 (OMIM 113705) and BRCA2 (OMIM 600185) variants. The combined sample size for these studies consisted of 4835 indiv...

Lerner-Ellis(Jordan),Khalouei(Sam),Sopik(V... Expert Rev Anticancer Ther 2016-06-01

...BRCA1 (5.3%) and BRCA2 (3.6%) and was lowest in PTEN (0.1%), CDH1 (0.1%) and STK11 (0.01%). After BRCA1/2, the prevalenc...

Fukuda(Takayo),Tsuruga(Tomoko),Kuroda(Taka... Curr Cancer Drug Targets 2016-10-19

...BRCA1 interacts with BARD1 to constitute a RING heterodimer-type E3 ubiquitin ligase. BRCA1-associated protein 1 (BAP1) ...

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