Atipairin(Apichart),Canyuk(Bhutorn),Ratana... J Biol Inorg Chem 2011-05-11

...BARD1 RING domains exhibited a substantial ubiquitin ligase activity compared with a defective complex containing the C6...

Nazeer(F I),Devany(E),Mohammed(S),Fonseca(... Oncogene 2011-09-15

...BARD1 and the 3' processing factor cleavage-stimulation factor 1 (CstF1). We found that p53 can coexist in complexes wit...

Capasso(Mario),Devoto(Marcella),Hou(Cuipin... Nat Genet 2010-11-04

...BARD1 nonsynonymous SNPs. These data show that common variation in BARD1 contributes to the etiology of the aggressive a...

Thanassoulas(Angelos),Nomikos(Michail),The... Biochim Biophys Acta 2010-10-18

...BARD1) is the heterodimeric partner of BRCA1. The BRCA1/BARD1 complex demonstrates ubiquitin ligase activity and has bee...

Irminger-Finger(Irmgard) Gynecol Oncol 2010-04-19

...BARD1, a protein that interacts with the breast cancer gene product BRCA1, is a promising candidate for fulfilling these...

Morris(Joanna R),Boutell(Chris),Keppler(Me... Nature 2010-02-01

...BARD1 heterodimer greatly increases its ligase activity, identifying it as a SUMO-regulated ubiquitin ligase (SRUbL). Fu...

Wu-Baer(Foon),Ludwig(Thomas),Baer(Richard) Mol Cell Biol 2010-06-01

...BARD1 polypeptide to form a heterodimeric BRCA1/BARD1 complex that catalyzes autoubiquitination of BRCA1 and trans ubiqu...

Nelson(Andrew C),Holt(Jeffrey T) Radiat Res 2010-09-03

...BARD1 and BACH1, which are important for DNA repair. This failure occurs despite the continued ability of the RING mutan...

Thakar(Amit),Parvin(Jeffrey D),Zlatanova(... J Biomol Struct Dyn 2010-02-12

...BARD1 complex in vitro. Here we demonstrate that the BRCA1/BARD1 complex can ubiquitylate both free H2A and H2B histones...

Brodie(Kirsty M),Henderson(Beric R) Cell Signal 2010-02-03

...BARD1 can shuttle between nucleus and cytoplasm. In this study, we evaluated the localisation patterns of BRCA1 and BARD...