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The Contribution of Genetic Modifiers to Ovarian Cancer Risk in BRCA1 and BRC...

Cylwik(D),Dwornik(R),Białkowska(K) Cancers (Basel) 2026-01-23

...BARD1, MRE11, RAD51, and 9p22.2. The analysis identified 11 variants affecting both BRCA1 and BRCA2 carriers, most of wh...

CTCF primes repressive chromatin for rapid BRCA1/BARD1 recruitment to drive h...

Hwang(SY),Choi(D),Choi(MJ),Jo(HR),Jeong(JH... Nucleic Acids Res 2026-07-17

...BARD1 play key roles in HR. However, whether and how CTCF cooperates with BRCA1/BARD1 for HR remain poorly understood. H...

[Hereditary breast cancer : Syndromes, pathology, clinical aspects].

Lebeau(A),Schmutzler(R) Pathologie (Heidelb) 2026-09-00

...BARD1) and genes associated with classic tumor predisposition syndromes (TP53, PTEN, STK11, CDH1, NF1) are associated wi...

Optimizing GRIDSS for clinical use: A targeted NGS filtering strategy for ger...

Munté(E),Rofes(P),Millán-Castillo(M),Solan... Eur J Hum Genet 2026-03-16

...BARD1, and five mobile element insertions in APC, BRCA2, and PALB2. Altogether, GRIDSS implementation increased diagnost...

Fisetin-loaded nanoparticles as a novel approach for cholesterol regulation i...

Zhang(Z),Chen(X),Hu(X),Liang(J),Huang(H),L... J Nanobiotechnology 2026-02-27

...BARD1 pathway. Notably, ASGR1 overexpression counteracts fisetin's cholesterol-lowering effects. Additionally, carboxyme...

BARD1 and breast cancer genetic predisposition: case-control study and HRD si...

Reveneau(MF),De Pauw(A),Masliah-Planchon(J... Breast Cancer 2026-09-00

...BARD1 gPV and breast cancer while exploring the role of BARD1 in mammary oncogenesis. In this case-control study, 7,309 ...

The Impact of Conventional Chemotherapy Regimens and Targeted Drugs on Ovaria...

Haskoylu(S),Sahin(SB),Altıntas(A),Yildiz(S... Reprod Sci 2026-04-00

...BARD1, RAD51C, RAD51D, and TP53) to chemotherapy-induced gonadotoxicity remains unclear. Although animal data shows depl...

BPHL promotes TNBC stemness by resolving R-loops via POLR2A lactylation inhib...

Yuan(Q),Zhang(H),Zhang(N),Qian(Y),Hong(Z),... Cancer Lett 2026-05-01

...BARD1-mediated ubiquitination to resolve R-loops and enable β-catenin nuclear translocation, thereby perpetuating Wnt si...

Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical ...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... Cancers (Basel) 2026-08-29

...BARD1, and BRIP1 (one case each). Furthermore, 56 VUS were identified; among them, 7 were prioritized based on in silico...

Genomic Landscape of 6597 Hong Kong HBOC Patients: Implications for Beyond-BR...

Kwong(A),Ho(CYS),Tey(SK),Au(CH),Ma(ESK) Int J Mol Sci 2026-08-24

...BARD1. New cancers or recurrences were detected during their surveillance; the overall pick up rates were 8.3% (PALB2), ...

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