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TP53 BRCA1 CRISPR single-cell cancer

Soo Lee(Nam),Jin Chung(Hee),Kim(Hyoung-Jun... Nat Commun 2016-05-23

...BRCA1, at DNA lesions. Conversely, accumulation of TRAIP is normal in RAP80-depleted cells, implying that TRAIP acts ups...

Wang(Qiang),Wang(Xiaoying),Tian(Xiufen),Ta... J Mol Histol 2016-10-31

...BRCA1, IGFBP, and integrin, and involved in organ differentiation, development, cell apoptosis, and carcinogenesis. Rece...

Chang(Yaojen),Near(Aimee M),Butler(Karin M... J Oncol Pract 2016-10-20

BRCA1/2 counseling and mutation testing is recommended for high-risk women, but geographic barriers exist, and no data o...

Laderas(Ted G),Heiser(Laura M),Sönmez(Kema... Front Genet 2016-01-18

...BRCA1 and ESR1, lending credence to this approach. In addition, using Random Forest Classifiers, we show that these sign...

Siu(Albert L), Ann Intern Med 2016-06-22

...BRCA1 or BRCA2 gene mutation or other familial breast cancer syndrome) or a history of chest radiation at a young age.,T...

Andrici(Juliana),Goeppert(Benjamin),Sioson... Medicine (Baltimore) 2016-05-31

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP...

Abdul Rasheed(P),Sandhyarani(N) Anal Chim Acta 2016-08-15

A mass sensitive quartz crystal microbalance (QCM) based genosensor has been developed using breast cancer 1 (BRCA1) gen...

Ławniczak(Małgorzata),Jakubowska(Anna),Bia... Hered Cancer Clin Pract 2016-01-18

...BRCA1 Polish founder mutations (5382insC, C61G and 4153delA) as well as for 9 known recurrent mutations in BRCA1 and BRC...

Du(Yi),Yamaguchi(Hirohito),Wei(Yongkun),Hs... Nat Med 2016-06-27

...BRCA1 and BRCA2 have essential roles in repairing DNA double-strand breaks, and a deficiency of BRCA proteins sensitizes...

Palmbos(Phillip L),Hussain(Maha H) Oncology (Williston Park) 2016-07-01

...BRCA1, BRCA2, or ATM. Emerging data suggest that drugs that target poly(adenosine diphosphate [ADP]-ribose) polymerase (...

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