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Metastasis of Pregnancy-Associated Breast Cancer (Suspected to Be Hereditary ...

Okuda(Tomohiro),Yamamoto(Sakura),Matsuo(Se... Case Rep Obstet Gynecol 2016-03-16

...BRCA1/2, though genetic counseling was provided. In cases of pregnancy-related breast cancer, consideration must be give...

Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequen...

Tung(Nadine),Lin(Nancy U),Kidd(John),Allen... J Clin Oncol 2016-11-10

Testing for germline mutations in BRCA1/2 is standard for select patients with breast cancer to guide clinical managemen...

RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Ess...

Hodge(Curtis D),Ismail(Ismail H),Edwards(R... J Biol Chem 2016-11-10

...BRCA1. Chromatin-targeted RNF168 rescues 53BP1 recruitment involved in non-homologous end joining but not BRCA1 recruitm...

NBR1 enables autophagy-dependent focal adhesion turnover.

Kenific(Candia M),Stehbens(Samantha J),Gol... J Cell Biol 2016-07-11

...BRCA1 (NBR1) as a key mediator of autophagy-dependent FA remodeling. NBR1 depletion impairs FA turnover and decreases ta...

A Case of Metaplastic Breast Cancer with Prolonged Response to Single Agent L...

Hamad(Lamya),Khoury(Thaer),Vona(Karen),Nes... Cureus 2016-02-26

...BRCA1 gene. Approximately seven months after a left mastectomy, the patient presented with biopsy-proven metastatic dise...

Prolactin inhibits a major tumor-suppressive function of wild type BRCA1.

Chen(Kuan-Hui Ethan),Walker(Ameae M) Cancer Lett 2016-08-24

...BRCA1, markedly increase the risk of breast and ovarian cancer, most breast and ovarian cancers express wild type BRCA1....

Gene and pathway level analyses of germline DNA-repair gene variants and pr...

Saunders(Edward J),Dadaev(Tokhir),Leongamo... Br J Cancer 2016-08-24

...BRCA1 give rise to moderately elevated risk, whereas two of B100 common, low-penetrance PrCa susceptibility variants ide...

Incidence of BRCA1 somatic mutations and response to neoadjuvant chemotherapy...

Li(Manxiu),Zhang(Juan),Ouyang(Tao),Li(Jinf... Gene 2016-08-26

...BRCA1 somatic mutations and to investigate the association between BRCA1 deleterious somatic mutation status and respons...

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsive...

Liu(Ying),Pike(Malcolm C),Wu(Nancy),Lin(Yv... PLoS One 2016-06-07

...Brca1 to follow up on our earlier observation that absence of a functional Brca1 in these important regulators of menstr...

Risk prediction model for epithelial ovarian cancer using molecular markers a...

Zhang(Meiying),Zhuang(Guanglei),Sun(Xiangj... J Ovarian Res 2016-08-02

...BRCA1), murine sarcoma viral oncogene homolog B (BRAF) and Kirsten rat sarcoma viral oncogene homolog (KRAS).,Our synthe...

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