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Risk of Second Primary Malignancy in Breast Cancer Survivors: A Nested Popula...

Marcheselli(Raffaella),Marcheselli(Luigi),... J Breast Cancer 2016-01-15

...BRCA1 or BRCA2 mutation, human epidermal growth factor receptor 2 (HER2)+ status, chemotherapy, and radiotherapy were re...

Association of polymorphisms with a family history of cancer and the presence...

Fernandes(Gabriela C),Michelli(Rodrigo A D... Hered Cancer Clin Pract 2016-01-15

...BRCA1/2 genes; Group 2: women with variants of uncertain significance in BRCA1/2 and Group 3: women with no mutations in...

Hormone replacement therapy after menopause and risk of breast cancer in BRCA...

Kotsopoulos(Joanne),Huzarski(Tomasz),Gronw... Breast Cancer Res Treat 2016-10-14

Many BRCA1 mutation carriers undergo elective surgical oophorectomy (often before menopause) to manage their elevated ri...

Investigating the effect of 28 BRCA1 and BRCA2 mutations on their related tra...

Quiles(Francisco),Menéndez(Mireia),Tornero... Breast Cancer Res Treat 2016-10-14

Germline inactivating mutations in the BRCA1 and BRCA2 genes are responsible for hereditary breast and ovarian cancer sy...

TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.

Soo Lee(Nam),Jin Chung(Hee),Kim(Hyoung-Jun... Nat Commun 2016-05-23

...BRCA1, at DNA lesions. Conversely, accumulation of TRAIP is normal in RAP80-depleted cells, implying that TRAIP acts ups...

Four and a half LIM domains 2 contributes to the development of human tongue ...

Wang(Qiang),Wang(Xiaoying),Tian(Xiufen),Ta... J Mol Histol 2016-10-31

...BRCA1, IGFBP, and integrin, and involved in organ differentiation, development, cell apoptosis, and carcinogenesis. Rece...

Economic Evaluation Alongside a Clinical Trial of Telephone Versus In-Person ...

Chang(Yaojen),Near(Aimee M),Butler(Karin M... J Oncol Pract 2016-10-20

BRCA1/2 counseling and mutation testing is recommended for high-risk women, but geographic barriers exist, and no data o...

A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensi...

Laderas(Ted G),Heiser(Laura M),Sönmez(Kema... Front Genet 2016-01-18

...BRCA1 and ESR1, lending credence to this approach. In addition, using Random Forest Classifiers, we show that these sign...

Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendati...

Siu(Albert L), Ann Intern Med 2016-06-22

...BRCA1 or BRCA2 gene mutation or other familial breast cancer syndrome) or a history of chest radiation at a young age.,T...

Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma.

Andrici(Juliana),Goeppert(Benjamin),Sioson... Medicine (Baltimore) 2016-05-31

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP...

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