Breast cancer susceptibility gene 1 (BRCA1) was first identified in 1994 and has since been shown to encode a tumor supp...
The contribution of BRCA1 (breast cancer 1) to the repair of broken DNA is well established, but its real role at the mo...
...BRCA1, CTIP, and RAD51 at DSB sites, may play a critical role in the crosstalk between chromatin compaction and DSB repa...
...BRCA1 and BRCA2) that occurred in patients with a family history was investigated. We studied published articles about m...
...BRCA1-mediated homologous recombination (HR) repair in G1 phase. In contrast, BRCA1 antagonizes 53BP1-direct NHEJ repair...
...BRCA1/BRCA2, mismatch repair genes, and other genes in the homologous recombination/DNA repair pathway propelled the gen...
...BRCA1 and a nonsense mutation in exon 25 of in BRCA2 were detected in one patient each. Both patients belonged to lumina...
Cells deficient in the Brca1 and Brca2 genes have reduced capacity to repair DNA double-strand breaks by homologous reco...
In this study, we investigated the contribution of a gene expression-based signature (composed of BAG1, BRCA1, CDC6, CDK...
...BRCA1 and BRCA2 are responsible for most of the known causes of HBOC, while mutations in mismatch repair genes and sever...
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