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TP53 BRCA1 CRISPR single-cell cancer

Zhang(Wenwen),Luo(Jiayan),Chen(Fengxia),Ya... Oncotarget 2016-05-02

...BRCA1 and/or PIG3 and overall survival (OS). Moreover, we reveal that overexpression of BRCA1 significantly increased ex...

Shiovitz(S),Korde(L A) Ann Oncol 2016-04-05

...BRCA1, BRCA2, PTEN, TP53, CDH1, and STK11), which confer up to an 80% lifetime risk of breast cancer. An additional 2%-3...

Trottier(M),Lunn(J),Butler(R),Curling(D),T... Clin Genet 2016-04-25

...BRCA1 and BRCA2 mutations among unselected breast cancer patients in the Bahamas is 23%. It is beneficial to advise rela...

Andersen(M Robyn),Thorpe(Jason),Buist(Dian... Behav Med 2016-10-19

...BRCA1 or BRCA2 are at substantially elevated risk for ovarian cancer. To understand what percentage of women with high-r...

Albarakati(Nada),Abdel-Fatah(Tarek M A),Do... Mol Oncol 2016-02-17

BRCA1, a key factor in homologous recombination (HR) repair may also regulate base excision repair (BER). Targeting BRCA...

Petrucelli(Nancie),Mange(Sarah),Fulbright(... J Genet Couns 2016-05-05

This study determined the prevalence of non-Ashkenazi Jewish BRCA1/2 mutations in the Ashkenazi Jewish population in the...

Ho Quoc(C),Faure(C),Carrabin(N),Istasse(F)... J Gynecol Obstet Biol Repro... 2016-02-23

...BRCA1, and a case of insufficient margins). We realized 12 cases of controlateral surgery at the same time for symmetry....

Sopik(V),Phelan(C),Cybulski(C),Narod(S A) Clin Genet 2016-01-04

...BRCA1 and BRCA2 mutations for colorectal cancer. Accurate knowledge of colorectal cancer risk in BRCA1/2 carriers is imp...

de la Fouchardière(A),Cabaret(O),Savin(L),... Clin Genet 2016-05-10

...BRCA1-associated protein 1 (BAP1) gene encodes a nuclear deubiquitin enzyme which acts as a tumour suppressor. Loss of f...

Wang(C),Zhang(J),Wang(Y),Ouyang(T),Li(J),W... Ann Oncol 2016-08-18

...BRCA1 or BRCA2 mutation, respectively. The BRCA1/2 mutation rates were 10.5% and 3.0% among the patients who were diagno...

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