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Development and Real-World Evaluation of a Statewide Mainstream Model of Germ...

Jennings(CA),Cornthwaite(K),Osborn(M),Kich... Asia Pac J Clin Oncol 2026-02-00

...BRCA1/BRCA2 and mismatch repair (MMR) genes across South Australia. Participatory action research (PAR) and implementati...

g BRCA1 and g BRCA2 mutations in specific different domains affect ovarian ca...

Zhu(Y),Wang(Y),Shen(Z),Shen(L),Liu(H),Xian... Chin Med J (Engl) 2026-06-20

...BRCA1/2 mutations (g BRCA1/2 m) in ovarian cancer is controversial, and the clinical implications of specific mutation d...

β-TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1.

Jiménez-Guerrero(R),Belmonte-Fernández(A),... Mol Oncol 2026-02-00

...BRCA1 and CtIP, proteins involved in DNA damage repair by homologous recombination. We showed that SCF(β-TrCP) plays a k...

Real-World Outcomes of Olaparib Treatment in Japanese Patients With Metastati...

Yasuda(Y),Yoshida(S),Yonese(I),Sano(Y),Mat... Int J Urol 2026-08-00

...BRCA1/2 variants identified by comprehensive genomic profiling or BRCA-specific testing (BRACAnalysis). Disease progress...

Targeted Therapy in Pancreatic Ductal Adenocarcinoma: Current Advances and Ch...

Habib(R),Arnold(E),Obi(T),Vizeacoumar(FJ),... Curr Oncol 2026-07-28

...BRCA1 or BRCA2 pathogenic variants, immune checkpoint inhibition for mismatch repair-deficient or microsatellite instabi...

Surgical Management of Early-Onset Breast Cancer Among Young BRCA1 and BRCA2 ...

Wong(SM),Blondeaux(E),Delucchi(V),Coussy(F... JAMA Netw Open 2026-08-03

...BRCA1 or BRCA2 (BRCA1/2) carriers diagnosed with early-onset breast cancer. The BRCA BCY Collaboration is an internation...

Risk-Reducing Interventions in Women With Pathogenic Variants in Breast Cance...

Russell(EM),Nielsen(SM),Ellsworth(RE),Chwa... JCO Precis Oncol 2026-08-00

...BRCA1/2 versus other breast cancer susceptibility genes had higher odds of risk-reducing mastectomy (cancer-free: odds r...

Identification and Computational Analysis of BRCA1 Variants in Mexican Women ...

Gallegos-Arreola(MP),Garibaldi-Ríos(AF),Dá... Med Sci (Basel) 2026-08-01

...BRCA1 gene markedly increase the risk of developing them. Despite existing studies, the frequency and spectrum of BRCA1 ...

iPSC models of hereditary cancer predisposition: Mechanistic insights into pr...

Gan(BB),Yang(QB),Li(WL),Xu(N) Biochim Biophys Acta Rev Ca... 2026-08-26

...BRCA1/2/PALB2-, MMR-, TP53- and APC-associated models. Collectively, these systems show that lineage state, contextual s...

Risk-reducing gynecologic surgery in non-BRCA cancer predisposition mutations...

Mubeen(A),Dhall(D),Sharma(AE) Int J Gynecol Cancer 2026-08-07

...BRCA1/2 mutation carriers. This multi-institutional, institutional review board-approved retrospective study included pa...

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