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TP53 BRCA1 CRISPR single-cell cancer

Margan(Madalin Marius),Jitariu(Andreea Adr... J Breast Cancer 2016-07-06

...BRCA1. The consecutive loss of the BRCA1 gene leads to various abnormalities in epithelial cells. Normal breast epitheli...

Maeshima(Yurina),Oseto(Kumiko),Katsuragi(R... J Breast Cancer 2016-07-06

...BRCA1/2 mutations have a high risk of breast cancer and may opt for risk-reducing mastectomy (RRM). We report a 38-year-...

Nilov(D K),Tararov(V I),Kulikov(A V),Zakha... Acta Naturae 2016-07-20

...BRCA1-deficient breast cancer cells induced by cisplatin and doxorubicin, the widely used DNA-damaging chemotherapeutic ...

Pritchard(Colin C),Mateo(Joaquin),Walsh(Mi... N Engl J Med 2016-08-18

...BRCA1 (6 [0.9%]), RAD51D (3 [0.4%]), and PALB2 (3 [0.4%]). Mutation frequencies did not differ according to whether a fa...

Lopez(Veronica Aedo),Stravodimou(Athina),U... Rev Med Suisse 2016-07-26

...BRCA1 and BRCA2 are found in only a minority of breast cancer patients, their impact for those patients is important. It...

Tercyak(Kenneth P),Silber(Elana),Johnson(A... Healthcare (Basel) 2016-07-15

...BRCA1/2 mutation prevalence in this population. Amidst calls for population-based screening for hereditary breast cancer...

Rashid(Muhammad U),Naeemi(Humaira),Muhamma... Hered Cancer Clin Pract 2016-07-14

...BRCA1 and BRCA2 genes or in mismatch repair (MMR) genes, such as MLH1 and MSH2. Women harboring deleterious mutations in...

Hosny(Marwa M),Sabek(Nagwan A),El-Abaseri(... Int J Breast Cancer 2016-07-14

...BRCA1 methylation, our preliminary findings suggest that methylation of BRCA1 may be involved in breast tumors initiatio...

Yılmaz(Nafiye Karakaş),Karagin(Peren Hatic... J Turk Ger Gynecol Assoc 2016-07-12

...BRCA1 and BRCA2 gene mutation. Therefore, in the present study, we aimed to investigate the role of BRCA1 and BRCA2 gene...

Xu(Guangzhong),Li(Kai),Zhang(Nengwei),Zhu(... Gastroenterol Res Pract 2016-07-12

...BRCA1, ARID3A, EHF, SOX10, ZNF263, FOXL1, FEV, GATA3, FOXC1, and FOXD1. Most of them were involved in the carcinogenesis...

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