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Stabilization of MCRS1 by BAP1 prevents chromosome instability in renal cell ...

Peng(Jingtao),Ma(Jian),Li(Weiguo),Mo(Ren),... Cancer Lett 2016-02-01

...BRCA1-associated protein-1 (BAP1) was identified as one of the most frequently mutated genes in ccRCC, suggesting that B...

NRF2/miR-140 signaling confers radioprotection to human lung fibroblasts.

Duru(Nadire),Gernapudi(Ramkishore),Zhang(Y... Cancer Lett 2016-02-01

...BRCA1-dependent activation of NRF2 through the inhibition of KEAP1 function, promoting the nuclear accumulation of NRF2,...

Current and emerging breast cancer biomarkers.

Sana(Maryam),Malik(Hassan Jameel) J Cancer Res Ther 2016-08-26

...BRCA1, BRCA2, p53, HER2-neu, cyclin D1, and cyclin E, which are briefly described in this review.

Chk1 phosphorylated at serine345 is a predictor of early local recurrence and...

Alsubhi(Nouf),Middleton(Fiona),Abdel-Fatah... Mol Oncol 2016-10-28

...BRCA1, γH2AX, BLM, WRN, RECQL5, PTEN] protein expression was correlated to time to early local recurrence. Pre-clinicall...

Advances in PARP inhibitors for the treatment of breast cancer.

Dizdar(Omer),Arslan(Cagatay),Altundag(Kadr... Expert Opin Pharmacother 2016-06-27

...BRCA1 and POLQ recruitment to sites of DNA repair. Breast cancer subgroups with germline BRCA mutations or non-mutationa...

High Levels of Nucleolar Spindle-Associated Protein and Reduced Levels of BRC...

Chen(Li),Yang(Liu),Qiao(Feng),Hu(Xin),Li(S... PLoS One 2016-06-08

...BRCA1 (HR = 0.383, 95% CI: 0.160-0.915, P = 0.031) were independent prognostic indicators of DFS in TNBC. A receiver ope...

Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 3...

Basu(N N),Ingham(S),Hodson(J),Lalloo(F),Bu... Fam Cancer 2016-08-26

BRCA1 and BRCA2 mutation carriers have an increased risk of contralateral breast cancer after primary breast cancer. Ris...

RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA...

Wang(Y),Deng(O),Feng(Z),Du(Z),Xiong(X),Lai... Oncogene 2016-08-15

...BRCA1, in a manner independent of its E3 ligase activity but depending on E2F1, a well-known transcription factor of BRC...

The important molecular markers on chromosome 17 and their clinical impact in...

Zhang(Wei),Yu(Yingyan) Int J Mol Sci 2015-02-23

...BRCA1 and HIC-1) or DNA double-strand break repair gene (RDM1) are located on chromosome 17. We searched the literature ...

[Analysis of the mutations of BRCA1 in 9 familiar breast cancer patients].

Deng(Shanming),Wang(Yi),Ke(Yang),Xu(Guangwei) Beijing Da Xue Xue Bao 2015-07-08

To analyze the mutations of BRCA1 in 9 Chinese familiar breast cancer patients.,Peripheral blood samples were obtained f...

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