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TP53 BRCA1 CRISPR single-cell cancer

Garcia(Khristofer),Blank(Jonathan L),Bouck... Mol Cancer Ther 2015-02-19

...BRCA1/BRCA2 pathways, chromatin modification, and transcription-coupled repair reduced the synergy between mitomycin C a...

Christou(Charita M),Hadjisavvas(Andreas),K... PLoS One 2015-01-20

...BRCA1 and for classifying VUS. We achieved strong protein expression of full-length BRCA1 in transiently transfected HEK...

Delgado-Díaz(M Rocío),Martín(Yusé),Berg(An... Mol Oncol 2015-02-21

...BRCA1 in response to genotoxic stress. However, focus formation of MDC1 and γH2AX, earlier events in this response, are ...

Martorano(Lisa M),Winkelmann(Richard R),Ce... Int J Dermatol 2015-01-07

...BRCA1-associated protein 1 (BAP1) gene. Such familial risks are important for dermatologists to recognize when screening...

Surowy(Harald Martin),Sutter(Christian),Mi... Breast Cancer Res Treat 2015-11-12

Variants of uncertain clinical significance (VUS) in the high-penetrance breast cancer susceptibility genes BRCA1 and BR...

Biunno(Ida),Aceto(Gitana),Awadelkarim(Khal... Fam Cancer 2015-06-16

...BRCA1 gene. However, the BRCA1 mutations associated with BC in Africa are scarcely characterized. We report here 33 BRCA...

Song(Honglin),Cicek(Mine S),Dicks(Ed),Harr... Hum Mol Genet 2015-03-30

...BRCA1 and BRCA2, with 84 EOC cases (3.8%) carrying a BRCA1 mutation and 94 EOC cases (4.2%) carrying a BRCA2 mutation. T...

Bodian(Dale L),McCutcheon(Justine N),Kothi... PLoS One 2015-01-13

...BRCA1, BRCA2, KRAS, TP53, and PTEN, highlights differences between germline variants and reported somatic mutations. The...

Zhao(Hongchang),Zhu(Min),Dou(Gelin),Zhao(H... Cell Cycle 2015-01-12

...BRCA1, RAD51, and the ubiquitinated DNA damage response factors. Taken together, our results demonstrate a novel functio...

Hanoch(Yaniv),Miron-Shatz(Talya),Rolison(J... Psychooncology 2015-08-03

...BRCA1/2 genetic test results. However, they encountered difficulties interpreting the uninformative and ambiguous BRCA1/...

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