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Genomic Landscape of Early-Onset Colorectal Cancer: A Comparative Analysis Wi...

Shin(JE),Lee(E),Ha(SY),Lim(SH),Cho(YB),Par... JCO Precis Oncol 2026-08-00

...BARD1, FAT1, HIST1H1C, and LRP1B, whereas canonical drivers showed no significant age-dependent trends. In metastatic di...

Risk-reducing gynecologic surgery in non-BRCA cancer predisposition mutations...

Mubeen(A),Dhall(D),Sharma(AE) Int J Gynecol Cancer 2026-08-07

...BARD1, and ATM) or in BRCA1/2 who underwent risk-reducing salpingectomy or salpingo-oophorectomy, with or without hyster...

Bard1-Mediated Regulation of Hnrnpa2b1 Ubiquitination and Protein Stability C...

Li(T),Rong(T),Shen(Z),Wei(Z),Chen(D),Zhong... CNS Neurosci Ther 2026-08-00

...Bard1 knockdown reduced the Hnrnpa2b1 ubiquitination, slowed Hnrnpa2b1 degradation, and restored Sptbn2 expression. Knoc...

Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A...

Foglizzo(M),Datta(A),Degtjarik(O),Perera(H... Nat Commun 2026-08-11

...BARD1 to form the BRCA1-A supercomplex, which recognises K63-linked ubiquitin chains at DNA damage sites. ARISC-RAP80 co...

Uncovering Hereditary Risk: Germline Homologous Recombination Repair Variant ...

Kapoor(A),Uthale(S),Chain(A),Rungta(A),Ano... JCO Glob Oncol 2026-08-00

...BARD1, RAD50, NBN, MRE11, and FANCC. Of 950 patients analyzed, 364 (38.3%) harbored variants in HRR genes, with 266 (28%...

CTCF primes repressive chromatin for rapid BRCA1/BARD1 recruitment to drive h...

Hwang(SY),Choi(D),Choi(MJ),Jo(HR),Jeong(JH... Nucleic Acids Res 2026-07-17

...BARD1 play key roles in HR. However, whether and how CTCF cooperates with BRCA1/BARD1 for HR remain poorly understood. H...

Functional assessment of protein variants in structured domains by fluorescen...

Mateu-Regué(À),Mariani(L),Bagger(FO),Bose(... Sci Rep 2026-01-02

...BARD1 and RBBP8, respectively. The results demonstrate that FCCS, whether applied to full-length BRCA1 in live cells and...

[Characteristics of uterine leiomyosarcoma: a clinicopathological and molecul...

Li(XY),Liu(CR) Zhonghua Bing Li Xue Za Zhi 2026-01-08

...BARD1, FANCE, ATM, CHEK2 etc. Thirteen cases showed loss of ATRX protein expression. Conclusions: Uterine leiomyosarcoma...

Tyrer-Cuzick Lifetime Risk Is Not Associated With Non-BRCA1/2 Pathogenic Vari...

Rao(D),Wernecke(C),Baron(L),Cai(S),Beitsch... Breast J None

...BARD1. Out of those with PVs, 52% had non-BRCA1/2 PVs with an average TC of 5.47%. A total of 102 patients (10.58%) had ...

Hereditary Risk Assessment of Cancer Using Clinical History in Patients Diagn...

Tholia(H),Pandey(V),Gangadevi(P),Pareek(P) Ann Afr Med 2026-01-21

...BARD1, RAD51D, RAD51C, or BRIP) with the selected sociodemographic and clinical variables. Genetic counseling and testin...

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