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Zuo(K),Chen(Z),Lu(R),Liu(X),Liu(J) Ecotoxicol Environ Saf 2026-02-00

...BRCA1 promoter activity. Collectively, PBX1 attenuates MeHg-induced apoptosis in SH-SY5Y cells by inhibiting ROS accumul...

Westin(SN),Moore(K),Chon(HS),Pepin(JT),Sal... Gynecol Oncol 2026-03-00

...BRCA1/BRCA2 genes, homologous recombination repair genes, DNA polymerase epsilon and tumour protein 53 [TP53m]) were eva...

Paiella(S),Secchettin(E),Archibugi(L),De L... United European Gastroenter... 2026-02-00

...BRCA1/2, PALB2, BRIP1). Notably, 8 out of 17 (47%) of ATM, BRCA1/2, PALB2 carriers would not have met the national testi...

Matsubayashi(H),Kiyozumi(Y),Ishihara(E),Ha... Jpn J Clin Oncol 2026-05-07

...BRCA1 [6], APC [1], ATM [1], BAP1 [1], CDK4 [1], CDKN2A [1], MSH2 [1], and RAD51C [1]. The 23 patients with GPVs had 43 ...

Kubota(J),Masuda(S),Makazu(M),Kimura(K),Im... Clin J Gastroenterol 2026-04-00

...BRCA1/2 mutations, which are established targets in pancreatic ductal adenocarcinoma (PDAC), remains unclear in APC. We ...

Hussain(MM),Qammar(S),Wang(JM),Zhai(AQ),Li... J Gastroenterol Hepatol 2026-03-00

...BRCA1/2 mutation carriers and individuals with Lynch syndrome, have demonstrated increased detection of Stage I PDAC, of...

Funada(E),Nomura(H),Kon(T),Kuratomi(Y),Wat... J Egypt Natl Canc Inst 2026-02-16

...BRCA1/2 germline pathogenic variants (gPV). METHODS: Patients with genetically confirmed BRCA1/2 gPV diagnosed with ovar...

He(ML),Wang(ZH),Yao(X),Ye(LL),Du(BQ),Wang(... J Enzyme Inhib Med Chem 2026-12-00

...BRCA1/2-mutated breast cancer but show limited efficacy in wild-type cancers and face resistance issues. To overcome the...

de Souza Wagner(PH),Freitas Uchôa Matheus(... Fam Cancer 2026-02-16

BACKGROUND: BRCA1/2-carriers—who account for 5–10% of breast cancer (BC) cases—face markedly elevated lifetime risks of ...

Paksoy(B),Erkal(O),Kocaaga(A) Clin Transl Oncol 2026-08-00

Targeted multigene panel testing is increasingly used to assess hereditary cancer susceptibility beyond BRCA1/2. However...