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Mitochondrial toxins cause widespread downregulation of pathways in X-linked dy…

Grütz(K),Künstner(A),Krause(C),Santinelli(L)… Stem Cell Reports 2026-06-09

...TAF1 gene. TAF1 encodes the TATA-box binding protein-associated factor 1, the largest subunit of the basal transcription...

Alterations in energy production in a Drosophila model for the X-linked dystoni…

Mandik(F),Algodon(SM),Seibler(P),Klein(C),Vo… Front Aging Neurosci None

...Taf1 deficiency and performed a pilot RNA sequencing analysis. Subsequently, we validated these findings in Taf1-deficie...

An integrated machine learning framework for developing a transcriptomic analys…

Lu(F),Yang(F),Yang(W) Medicine (Baltimore) 2026-01-23

...TAF1) was constructed. This study established a novel molecular framework linking gout pathogenesis with sleep disruptio...

Downregulation of SLC12A5 in glioblastoma multiforme: a novel prognostic biomar…

Zhong(R),Kou(Z),Wang(H),Li(Q),Xiao(Y),Li(Z),… Naunyn Schmiedebergs Arch Pha… 2026-04-00

...TAF1, and lapatinib) that targeted SLC12A5-related pathways. Crucially, multivariate Cox regression analysis confirmed t...

Abidi Syndrome and Another Family With X-Linked Intellectual Disability Have TA…

Han(M),Abidi(F),Skinner(C),Srikanth(S),Wang(… Am J Med Genet A 2026-08-04

Genetic alterations in TATA box binding protein-associated factor 1 (TAF1) have been found in an X-linked intellectual d...

m6A-Modulated RNF14 Favors Fatty Acid Oxidation to Drive Colorectal Cancer Prog…

Lv(L),Lv(F),Li(B),Li(G),Yi(H) FASEB J 2026-06-30

...TAF1) protein stability via promoting its ubiquitination. Moreover, TAF1 bound to PTEN-induced kinase 1 (PINK1) promoter...

Single-molecule imaging reveals RNA polymerase II dynamics and TAF1-dependent p…

Haque(N),Cutler(R),Sidoli(S),Coleman(RA) Nat Commun 2026-06-20

...TAF1 reduces RNA polymerase II clustering and increases the global pausing index, supporting a model in which TAF1 promo...

A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator …

Burgos(SD),Ward(AM),Ashokkumar(M),Enders(KP)… mBio 2026-07-08

...TAF1, but not BRD1, is essential for maintaining HIV latency and that TAF1 depletion selectively increases HIV transcrip...

Synthesis and characterization of a novel phosphatidylinositol 5-phosphate (PI(…

Brodie(G),Sayed(A),Kreuz(S),Fischle(W),Conwa… RSC Chem Biol 2026-07-08

...TAF1 proteins that are known PI(5)P-interacting factors. Copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemi...

Infantile Epileptic Spasm Syndrome Caused by TAF1 Missense Variants: Expanding …

Xiao(H),Xie(C),Peng(P),Ni(X),Mao(L),Peng(J) Hum Mutat 2026-00-00

...TAF1 missense variants (c.236C > A, p.T79N; c.4771G > A, p.D1591N) in the two patients. Both novel TAF1 missense variant...

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