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TAF1 Suppresses MHC-I Expression and Correlates with Poor Immunotherapy Respons…

Gao(Q),Wei(K),Pan(D),Xi(Y),Xu(C),Jia(D) Biomedicines 2026-04-23

...TAF1 expression was inversely correlated with MHC-I expression. Knockdown of TAF1 in SCLC cells restored MHC-I expressio...

Alterations in energy production in a Drosophila model for the X-linked dystoni…

Mandik(F),Algodon(SM),Seibler(P),Klein(C),Vo… Front Aging Neurosci None

...Taf1 deficiency and performed a pilot RNA sequencing analysis. Subsequently, we validated these findings in Taf1-deficie...

Abidi Syndrome and Another Family With X-Linked Intellectual Disability Have TA…

Han(M),Abidi(F),Skinner(C),Srikanth(S),Wang(… Am J Med Genet A 2026-08-04

Genetic alterations in TATA box binding protein-associated factor 1 (TAF1) have been found in an X-linked intellectual d...

Pinoresinol as a Potential c-Myc Complex Modulator: An In Silico Study.

Villanueva-Castillo(A),Mancilla-Simbro(C),Vi… Curr Issues Mol Biol 2026-08-17

...TAF1 (TATA-binding protein (TBP)- Multiple direct interactions of TBP with the MYC oncoprotein) transcriptional complex ...

The Clinical, Genetic, Psychosocial, and Care Landscape of X-Linked Dystonia-Pa…

Ramos(MD),Manning(J),Harris(J),Adorno(M),Mar… Am J Mens Health None

...TAF1 genetic mutation, and diagnosis takes years. Deep-brain stimulation reduced dystonia severity. Pharmacological ther...

A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator …

Burgos(SD),Ward(AM),Ashokkumar(M),Enders(KP)… mBio 2026-07-08

...TAF1, but not BRD1, is essential for maintaining HIV latency and that TAF1 depletion selectively increases HIV transcrip...

Synthesis and characterization of a novel phosphatidylinositol 5-phosphate (PI(…

Brodie(G),Sayed(A),Kreuz(S),Fischle(W),Conwa… RSC Chem Biol 2026-07-08

...TAF1 proteins that are known PI(5)P-interacting factors. Copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemi...

m6A-Modulated RNF14 Favors Fatty Acid Oxidation to Drive Colorectal Cancer Prog…

Lv(L),Lv(F),Li(B),Li(G),Yi(H) FASEB J 2026-06-30

...TAF1) protein stability via promoting its ubiquitination. Moreover, TAF1 bound to PTEN-induced kinase 1 (PINK1) promoter...

Single-molecule imaging reveals RNA polymerase II dynamics and TAF1-dependent p…

Haque(N),Cutler(R),Sidoli(S),Coleman(RA) Nat Commun 2026-06-20

...TAF1 reduces RNA polymerase II clustering and increases the global pausing index, supporting a model in which TAF1 promo...

Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals…

Capponi(S),Ehret(S),Camgöz(Z),Gather(F),Vain… Nat Commun 2026-05-05

...TAF1 locus, and that BRD4 depletion bypasses this premature termination checkpoint. These findings reveal new dimensions...

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