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The role of WT1 gene in neuroblastoma.

Wang(J),Oue(T),Uehara(S),Yamanaka(H),Oji(Y),… J Pediatr Surg 2011-02-00

...WT1 in the development of neuroblastoma (NB), we examined the WT1 expression in NB and the effect of WT1 suppression on ...

lncRNA WT1-AS is upregulated in osteoporosis and regulates the apoptosis of ost…

Wang(C),Xie(Q),Sun(W),Zhou(Y),Liu(Y) Exp Ther Med 2021-07-00

...WT1 antisense RNA (WT1-AS) and this protein serves an important role in osteoporosis. The present study aimed to investi...

WT1-mediated transcriptional activation is inhibited by dominant negative mutan…

Reddy(JC),Morris(JC),Wang(J),English(MA),Hab… J Biol Chem 1995-05-05

...WT1-binding sites, we found that WT1 isoforms (A) and (B) strongly activated transcription. WT1(A) and (B) bound equally...

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene…

Nilsson(HJ),Montano(G),Ullmark(T),Lennartsso… Oncotarget 2017-10-20

...WT1 in hematopoietic cells resulted in increased NAB2 levels, while suppression of WT1 decreased NAB2 expression. WT1 bo...

A WT1 protein-derived, naturally processed 16-mer peptide, WT1(332), is a promi…

Fujiki(F),Oka(Y),Kawakatsu(M),Tsuboi(A),Naka… Microbiol Immunol 2008-12-00

...WT1(332) is a naturally processed peptide. These results indicate that the natural peptide, WT1(332), is a promiscuous W...

WT1 regulates HOXB9 gene expression in a bidirectional way.

Schmidt(V),Sieckmann(T),Kirschner(KM),Scholz… Biochim Biophys Acta Gene Reg… 2021-00-00

...WT1 regulates the HOXB9 gene in a bidirectional manner. Silencing of WT1 activates HOXB9 in Wt1 expressing renal cell ad...

Antisense WT1 transcription parallels sense mRNA and protein expression in feta…

Moorwood(K),Charles(AK),Salpekar(A),Wallace(… J Pathol 1998-08-00

...WT1 sense mRNA and WT1 protein. Using strand-specific WT1 riboprobes, the expression of WT1 and the antisense message we...

WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrom…

Rosenfeld(C),Cheever(MA),Gaiger(A) Leukemia 2003-07-00

...WT1 in adults suggests that WT1 can be a target for leukemia/MDS therapy. WT1 expression in stem/progenitor cells remain...

WT1 (Wilms' tumor gene 1): biology and cancer immunotherapy.

Sugiyama(H) Jpn J Clin Oncol 2010-05-00

...WT1-targeted immunotherapy have confirmed its safety and clinical efficacy. WT1-specific cytotoxic T lymphocytes and WT1...

Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein…

Johnstone(RW),Wang(J),Tommerup(N),Vissing(H)… J Biol Chem 1998-05-01

...WT1 can modulate the function of WT1. Here, we report the identification and cloning of a novel WT1-interacting protein ...

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