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WT1-AS promotes cell apoptosis in hepatocellular carcinoma through down-regulat…

Lv(L),Chen(G),Zhou(J),Li(J),Gong(J) J Exp Clin Cancer Res 2015-10-13

...WT1-AS downregulates WT1 by binding to the TATA region of the WT1 promotor. WT1-AS was also able to reverse WT1-mediated...

Differential function of Wilms' tumor gene WT1 splice isoforms in transcription…

Hewitt(SM),Fraizer(GC),Wu(YJ),Rauscher(FJ),S… J Biol Chem 1996-04-12

...WT1 promoter. Repression of transcription by WT1 has been shown to require two WT1 binding sites. We examined WT1 repres...

Identification of two distinct populations of WT1-specific cytotoxic T lymphocy…

Fujiki(F),Tsuboi(A),Morimoto(S),Hashimoto(N)… Cancer Immunol Immunother 2021-01-00

...WT1-tetramerlow WT1-TCRlow CD5low and WT1-tetramerhigh WT1-TCRhigh CD5high CTLs were dominantly detected in WT1 CTL + WT...

Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 …

Ichinohasama(R),Oji(Y),Yokoyama(H),Takeuchi(… Cancer Sci 2010-05-00

...WT1 vaccine compared to RT-PCR, and the highly sensitive WT1 antibody, WT1-R, may be useful to detect WT1 protein in tum...

Truncated WT1 mutants alter the subnuclear localization of the wild-type protei…

Englert(C),Vidal(M),Maheswaran(S),Ge(Y),Ezze… Proc Natl Acad Sci U S A 1995-12-19

...WT1 and WT1 mutants, we observed dramatic differences in the subnuclear localization of the induced proteins. The WT1 is...

Analysis of WT1 mutations, expression levels and single nucleotide polymorphism…

Luo(S),Yu(K),Yan(QX),Shen(ZJ),Wu(JB),Chen(HM… Leuk Lymphoma 2014-02-00

...WT1 levels were higher in patients with WT1(GG) than in those with WT1(GA/AA). However, high levels of WT1 (> median) pr...

Association of WT1 IgG antibody against WT1 peptide with prolonged survival in …

Oji(Y),Hashimoto(N),Tsuboi(A),Murakami(Y),Iw… Int J Cancer 2016-09-15

...WT1 antibody remains unknown. Thus, we measured IgG antibody levels against the WT1-235 peptide (WT1-235 IgG antibody) i...

Wilms' tumor 1 gene (WT1) is overexpressed and provides an oncogenic function i…

Sangkhathat(S),Kanngurn(S),Chaiyapan(W),Grid… Oncol Lett 2010-07-00

...WT1 was performed in primary cultures of wild-type nephroblastoma using WT1 siRNA. The average WT1 expression level in n...

Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense o…

Yamagami(T),Sugiyama(H),Inoue(K),Ogawa(H),Ta… Blood 1996-04-01

...WT1 expression by WT1 antisense oligomers on the growth of the leukemic cells expressing WT1. When 20 different WT1 anti...

Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and s…

Dallosso(AR),Hancock(AL),Malik(S),Salpekar(A… RNA 2007-12-00

...WT1-AS), which we have previously found to regulate WT1 protein levels. In this study, we show that WT1-AS is present in...

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