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TP53 BRCA1 CRISPR single-cell cancer

Bell(K),Hodgson(N),Levine(M),Sadikovic(B),... Breast Cancer Res Treat 2015-08-18

...BRCA1 and p53. Genetic testing was requested on an expedited basis to assist in surgical decision-making and BRCA1/2 and...

McCubrey(James A),Davis(Nicole M),Abrams(S... Adv Biol Regul 2015-05-19

...BRCA1, TP53, PIK3CA, RB, P16INK1 and various miRs as well some drugs which are showing promise in targeting CICs. In add...

Lamparter(Christina),Winn(Louise M) Toxicol Sci 2015-10-23

...Brca1, and Brca2, with Western blotting used to quantify Rad51, cleaved caspase-3 and cleaved-PARP protein. Increased re...

Tanic(Miljana),Yanowski(Kira),Gómez-López(... Int J Cancer 2015-01-23

Screening for germline mutations in breast cancer-associated genes BRCA1 and BRCA2 is indicated for patients with breast...

Chen(X),Paranjape(T),Stahlhut(C),McVeigh(T... Oncogene 2015-07-27

...BRCA1 and 2). Recent findings indicate that there are powerful genetic markers of cancer risk outside of these regions, ...

Stebbing(J),Zhang(H),Xu(Y),Lit(L C),Green(... Oncogene 2015-07-27

...BRCA1 dependent shown by 3D-matrigel and soft agar assays. KSR1 stabilizes BRCA1 protein levels by reducing BRCA1 ubiqui...

Nicot(Anne-Sophie),Lo Verso(Francesca),Rat... Autophagy 2015-05-11

...BRCA1 gene 1) binds UB/ubiquitin and the autophagosome-conjugated MAP1LC3/LC3 (microtubule-associated protein 1 light ch...

Ow(Ghim Siong),Ivshina(Anna V),Fuentes(Glo... Cell Cycle 2015-12-15

...BRCA1/2 predispose to cancer in 9.5-13% of EOC patients. However, the overall burden of disease due to either inherited ...

Vollebergh(Marieke A),Lips(Esther H),Neder... Breast Cancer Res 2015-04-16

...BRCA1-mutated breast cancer closely and might also share this hypersensitivity. However, ways to identify HRD in non-BRC...

Pilewskie(Melissa),Morrow(Monica) Surg Oncol Clin N Am 2015-02-12

...BRCA1 or BRCA2 mutations, a family history suggesting a hereditary breast cancer syndrome, or a history of chest wall ra...

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