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TP53 BRCA1 CRISPR single-cell cancer

Massuti(Bartomeu),Sanchez(Jose Miguel),Her... Transl Lung Cancer Res 2015-03-25

...BRCA1) are among the most promising potential biomarkers for early disease and their clinical utility is currently being...

Wang(Xiemei),Li(Shaolin) Int J Mol Med 2015-12-01

...BRCA1 and ESR1. Overall, the results of the present study suggested an association between p300 and carcinogenic genes. ...

Nahleh(Zeina),Otoukesh(Salman),Dwivedi(Alo... Am J Cancer Res 2015-01-28

...BRCA1 mutations and five had BRCA2 mutations. A total of 17 deleterious BRCA Mutations were observed. Seven have been pr...

Heemskerk-Gerritsen(B A M),Seynaeve(C),van... J Natl Cancer Inst 2015-04-27

...BRCA1/2 mutation carriers, but may have been subject to several types of bias. The purpose of this nationwide cohort stu...

Galiatsatos(Polymnia),Rothenmund(Heidi),Au... Dig Dis Sci 2015-09-30

...BRCA1 or BRCA2 mutations, but there is a paucity of literature looking at psychosocial impact of LS testing for probands...

Omoto(Yoko),Takeshita(Takashi),Yamamoto(Yu... Springerplus 2015-03-16

...BRCA1 was significantly up-regulated by EE2 whereas nuclear staining tended to decrease. Individual comparisons suggeste...

Xu(Guotai),Chapman(J Ross),Brandsma(Inger)... Nature 2015-06-29

...BRCA1 is an important factor for this repair pathway. In the absence of BRCA1-mediated HR, the administration of PARP in...

Cheon(Jae Yeon),Mozersky(Jessica),Cook-Dee... Genome Med 2015-01-16

After two decades of genetic testing and research, the BRCA1 and BRCA2 genes are two of the most well-characterized gene...

Bigot(N),Guérillon(C),Loisel(S),Bertheuil(... Cell Death Dis 2015-09-11

...BRCA1 and RAD51. Here, we find that the ING1b tumor suppressor accumulates in adipose-derived stromal cells (ADSCs) upon...

Yao(Haiping),Ji(Ming),Zhu(Zhixiang),Zhou(J... Bioorg Med Chem 2015-10-05

...BRCA1/2 and PTEN, respectively, in comparison with homologous recombination proficient cell types such as breast cancer ...

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