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TP53 BRCA1 CRISPR single-cell cancer

Benada(Jan),Burdová(Kamila),Lidak(Tomáš),v... Cell Cycle 2015-09-18

...BRCA1 and 53BP1 are required for homologous recombination and non-homologous end joining, respectively. Whereas mechanis...

Martins(Filipe C),Santiago(Ines de),Trinh(... Genome Biol 2015-08-18

...BRCA1/2 mutations are the main drivers in high-grade serous ovarian carcinoma (HGSOC). We hypothesise that combining tis...

Cussenot(Olivier),Cancel-Tassin(Géraldine) Bull Cancer 2015-03-31

...BRCA1 gene, must be researched. In contrast, the genetic component of the majority of prostate cancer is polygenic, invo...

Laroche-Clary(A),Chaire(V),Le Morvan(V),Ne... Br J Cancer 2015-05-01

...BRCA1 haplotype was associated with trabectedin efficacy in soft-tissue sarcoma (STS) patients.,We analysed BRCA1 single...

Saelee(Pensri),Chaiwerawattana(Arkom),Ogaw... Asian Pac J Cancer Prev 2015-10-01

...BRCA1 promoter hypermethylation and expression in breast cancer cases. Sixty-one breast cancers were examined for BRCA1 ...

Lu(Daoyuan),Cai(Huan),Park(Sung-Soo),Siddi... Mol Cell Biol 2015-05-26

...BRCA1 in repair complexes; upregulation of repair proteins, including HMGN1 and RFC1; and regulation of poly(ADP-ribose)...

Cloud(Ann J),Thai(Ashley),Liao(Yuyan),Terr... Breast Cancer Res Treat 2015-09-28

...BRCA1 and/or BRCA2 carriers [HR 0.39, 95 % CI (0.16-0.97)]}. These results support that women at high risk, similar to w...

Yang(Xiaochen),Wu(Jiong),Lu(Jingsong),Liu(... PLoS One 2015-10-16

...BRCA1/2 mutation carriers, and their average onset age was much younger than patients with only BRCA1/2 mutations. Almos...

Arcand(Suzanna L),Akbari(Mohammed R),Mes-M... BMC Med Genet 2015-06-30

Specific germline mutations in the hereditary breast-ovarian cancer susceptibility (HBC/HBOC) genes, BRCA1, BRCA2 and PA...

Pelttari(Liisa M),Kiiski(Johanna I),Ranta(... Springerplus 2015-04-28

...BRCA1 and BRCA2 are specifically involved in the homologous recombination repair (HRR) of DNA double-strand breaks. A ce...

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