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TP53 BRCA1 CRISPR single-cell cancer

Taty-Taty(Gemael-Cedrick),Courilleau(Celin... Cell Cycle 2015-01-14

...BRCA1 recruitment around DSB or for HR in cooperation with Rad51. Recent data with 293T cells showed that mammalian H2A....

Eggington(J M),Bowles(K R),Moyes(K),Manley... Clin Genet 2015-05-12

...BRCA1/2 genes as a model. Our VCP has lowered the percentage of tests in which one or more BRCA1/2 variants of uncertain...

Underhill(Meghan L),Crotser(Cheryl B) J Genet Couns 2015-01-02

Recommendations for women with a deleterious BRCA1 or BRCA2 gene mutation include complex medical approaches related to ...

Chen(Ying),Bancroft(Elizabeth),Ashley(Sue)... Fam Cancer 2015-02-07

...BRCA1 and 87 BRCA2 carriers had RRBSO, with a further 26 BRCA1 carriers, 28 BRCA2 carriers and one non-carrier developin...

Soyombo(Abigail A),Wu(Yipin),Kolski(Lauren... Stem Cell Reports 2015-10-23

...BRCA1 5382insC mutant family. All BRCA1 5382insC heterozygous fibroblasts, iPSCs, and teratomas maintained equivalent ex...

Vassilopoulos(A),Chisholm(C),Lahusen(T),Zh... Oncogene 2015-04-28

...Brca1-mutant mouse model. Our data indicated that CSCs, which are enriched in CD24(+)CD29(+)/CD49f(+) cell population, d...

Marchetti(Claudia),Iadarola(Roberta),Palai... Menopause 2015-02-23

BRCA1/2 mutation carriers have greatly elevated lifetime risks of breast, ovarian, and fallopian tube cancers. Bilateral...

Marks(Jeffrey R) Breast Cancer Res 2015-05-18

...BRCA1 regulates this pathway. The relative contribution of this activity in BRCA1-associated tumorigenesis and DNA damag...

Finch(A),Bacopulos(S),Rosen(B),Fan(I),Brad... Clin Genet 2015-06-18

Genetic testing for BRCA1 and BRCA2 gene mutations, in conjunction with preventive salpingo-oophorectomy for mutation ca...

Hasan(Tarique Noorul),Shafi(Gowhar),Syed(N... Asian Pac J Cancer Prev 2015-01-21

...BRCA1) and breast cancer associated gene 2 (BRCA2) and the risk of breast cancer. TaqMan based Real Time Polymerase chai...

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