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TP53 BRCA1 CRISPR single-cell cancer

Childs(Erica J),Mocci(Evelina),Campa(Danie... Nat Genet 2015-10-26

...BRCA1 (ref. 5), STK11 (ref. 6), CDKN2A and mismatch-repair genes and low-penetrance loci are associated with increased r...

Neamatzadeh(Hossein),Shiryazdi(Seyed Mosta... J Res Med Sci 2015-06-25

BRCA1/2 genes mutation prevalence varies among ethnic groups and may be influenced by founder mutations. Understanding B...

Mori(Takahiro),Sumii(Makiko),Fujishima(Fum... Cancer Sci 2015-12-15

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that is involved in the regulation of cell growth. Recent...

Dkhissi(Fatima),Aggoune(Djamel),Pontis(Jul... Exp Hematol 2015-11-16

...BRCA1)-associated protein 1 (BAP1) is a deubiquitinase interacting with the DNA repair regulator BRCA1 and is frequently...

Vos(Janet R),Hsu(Li),Brohet(Richard M),Mou... J Clin Oncol 2015-10-26

...BRCA1/2 carriers.,The following methods to estimate the breast cancer risk of BRCA1/2 carriers were identified from the ...

Culler(Duane D),Silberg(Judy),Vanner-Nicel... J Genet Couns 2015-07-08

...BRCA1 and BRCA2 mutations represent the best-studied population undergoing genetic testing for cancer susceptibility. Ho...

Luo(Shukun),Xin(Xiaoran),Du(Li-Lin),Ye(Keq... J Biol Chem 2015-11-17

...BRCA1 C-terminal domain binds phosphorylated histone H2AX, and in its N terminus, a forkhead-associated (FHA) domain med...

Li(Hui),Giger(Maryellen L),Lan(Li),Janarda... J Med Imaging (Bellingham) 2015-07-09

...BRCA1/2 gene mutations, 75 with unilateral cancer, and 328 at low risk of developing breast cancer. Image-based phenotyp...

Kelly(Kimberly),Leventhal(Howard),Toppmeye... J Genet Couns 2015-07-08

...BRCA1/2 mutations. Most had a personal cancer history (N = 51; family only: N = 48); and received uninformative negative...

Clark(S),Bluman(L G),Borstelmann(N),Regan(... J Genet Couns 2015-07-08

...BRCA1/2 testing. When making a decision about genetic testing, study participants were concerned less about the potentia...

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