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Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multice...

Rebbeck(Timothy R),Mitra(Nandita),Domchek(... Cancer Res 2009-09-25

...BARD1, BRIP1, CTIP, MRE11, NBS1, RAD50, RAD51, and TOPBP1 in ovarian cancer risk. In BRCA1 carriers, no associations wer...

A comparison of BRCA1 nuclear localization with 14 DNA damage response protei...

Mok(Myth T S),Henderson(Beric R) Cell Signal 2009-12-14

...BARD1 are less mobile than 53BP1 at IR-induced nuclear foci. Our findings indicate that BRCA1-BARD1 and 53BP1 are proxim...

Structural basis for specific recognition of Lys 63-linked polyubiquitin chai...

Sato(Yusuke),Yoshikawa(Azusa),Mimura(Hisat... EMBO J 2009-09-16

...BARD1 complex to DNA-damage foci for DNA repair through specific recognition of Lys 63-linked polyubiquitinated proteins...

BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCH...

Han(Pei),Zhu(Yu-Xian) Plant Signal Behav 2009-11-23

...BARD1 was required for DNA repair. Recently, we find that AtBARD1 may function to confine WUS transcription in the shoot...

Characterization of the c.190T>C missense mutation in BRCA1 codon 64 (Cys64Arg).

Willems(P),Magri(V),Cretnik(M),Fasano(M),J... Int J Oncol 2009-07-20

...BARD1, essential for the tumor-suppressor activity of the BRCA1-BARD1 complex. By splicing site information analysis, ex...

Polymorphisms in HPV E6/E7 protein interacted genes and risk of cervical canc...

Zhou(Xiaoyi),Han(Suping),Wang(Sumin),Chen(... Gynecol Oncol 2009-07-07

Accumulating studies indicate that HPV E6/E7 oncoproteins interacting genes, TP53, BRCA1 and BARD1, play a critical role...

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquit...

Christensen(Devin E),Brzovic(Peter S),Klev... Nat Struct Mol Biol 2008-01-28

...BARD1 and the human E2s UbcH6, Ube2e2, UbcM2, Ubc13, Ube2k and Ube2w. All six E2s bind directly to the BRCA1 RING motif ...

Novel interaction between HPV E6 and BARD1 (BRCA1-associated ring domain 1) a...

Yim(Eun-Kyoung),Lee(Keun-Ho),Myeong(Jin),T... DNA Cell Biol 2008-01-18

...BARD1 degradation. A mutation assay revealed the site of interaction of E6 with BARD1. The effect of BARD1 on p53 transc...

BARD1 variants are not associated with breast cancer risk in Australian famil...

Gorringe(Kylie L),Choong(David Y H),Visvad... Breast Cancer Res Treat 2008-11-13

...BARD1 variants are associated with increased breast cancer risk. Using DHPLC analysis we screened the coding region of B...

Promotion of BRCA1-associated triple-negative breast cancer by ovarian hormones.

Lee(Eva Y-H P) Curr Opin Obstet Gynecol 2008-04-08

...BARD1 (BRCA1-associated RING domain) serve as an ubiquitin ligase for the monoubiquitination of estrogen receptor-alpha,...

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