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Homologous recombination deficiency (HRD) testing of high-grade serous carcin...

Demmer(I),Schmid(MB),Born(D),Handschin(G),... BJC Rep 2026-08-07

...BRCA1/2, and the HRD status based on BRCA1/2 mutational status and genomic instability metric (GIM). Concordance analysi...

Increased RHOA expression in peripheral blood mononuclear cells of patients w...

Khaki(M),Davoodian(N) Mol Biol Rep 2026-08-08

...BRCA1) were predicted to regulate RHOA mRNA expression. These findings suggest that RHOA upregulation in PBMCs may be as...

Dual Regulation of ACSL3 by TRIM33-Mediated Ubiquitination and NBR1-Dependent...

Yang(Y),Zhao(M),Feng(Y),Yu(H),Gong(Y),Liu(... Antioxid Redox Signal 2026-08-09

...BRCA1 gene 1 protein (NBR1). We further identified that tripartite motif-containing protein 33 (TRIM33), an E3 ubiquitin...

Mitochondria Dictate Progressive Versus Bimodal Aging of the Mammary Gland.

Jenkins(EC),Chattopadhyay(M),Mashaka(T),To... Aging Cell 2026-08-00

...BRCA1/2 mutations were proposed, they do not explain why the peaks are at 45 and 65, raising the possibility that the wa...

Current Advances of Molecular Biomarkers and Liquid Biopsies Techniques in Ov...

Zhang(J),Shan(W),Yu(J),Shi(H),Xu(Q),Shang(... Cancer Med 2026-08-00

...BRCA1/2-targeted therapy), minimal residual disease (MRD) detection, and monitoring of tumor evolution. CTCs, particular...

TFAP2A enhances radioresistance of non-small cell lung cancer by transcriptio...

Ma(J),Wang(F),Zhang(J),Tian(C),Bao(S),Yuan... Cell Oncol (Dordr) 2026-07-30

...BRCA1 promoter and transcriptionally activated BRCA1. BRCA1 restoration partially rescued the radiosensitizing effects a...

Hormone replacement therapy in healthy BRCA1 and 2 mutation carriers after ri...

Bounous(VE),Andronico(N),Lavalle(G),Suraci... Maturitas 2026-09-00

The management of menopausal symptoms in healthy women carrying BRCA1 or BRCA2 mutations is clinically challenging, part...

Somatic BRCA1 and BRCA2 detection in homologous recombination deficiency test...

Scaglione(GL),Roma(C),Califano(D),Cecere(S... Int J Gynecol Cancer 2026-06-20

To assess concordance of tumor BRCA1/BRCA2 variant detection across four sequencing workflows benchmarked against the My...

An Integrated Multi-Omics and Causal Inference Study Identifies a DNA Repair-...

Yang(J),Qiu(Z),Song(W),Liu(X),Wang(J),Yang(Y) Curr Med Chem 2026-07-30

...BRCA1 at both mRNA and protein levels in GC. These findings suggest that BRCA1 is not an independent prognostic factor b...

Chemotherapy type and survival in young BRCA1/2 carriers with HER2-negative e...

Bernstein-Molho(R),Sella(T),Delucchi(V),Co... Eur J Cancer 2026-09-09

...BRCA1/BRCA2 pathogenic variants (BRCA carriers) with early breast cancer (BC) is limited. We evaluated the association o...

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