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Genomic and non-genomic effects of glucocorticoids: implications for breast c...

Mitre-Aguilar(Irma B),Cabrera-Quintero(Alb... Int J Clin Exp Pathol 2015-12-03

...BRCA1 gene, a tumor suppressor gene that is mutated in the majority of patients with triple negative BC. Some clinical r...

Early-Onset Breast Cancer in a Family with Neurofibromatosis Type 1 Associate...

Jeon(Ye Won),Kim(Ra Mi),Lim(Seung Taek),Ch... J Breast Cancer 2015-04-02

...BRCA1 genes. Our findings indicate that an awareness of the possible concomitance of NF1 and BRCA1 gene mutations is imp...

Survival benefit in women with BRCA1 mutation or familial risk in the MRI scr...

Saadatmand(Sepideh),Obdeijn(Inge-Marie),Ru... Int J Cancer 2015-10-06

Adding MRI to annual mammography screening improves early breast cancer detection in women with familial risk or BRCA1/2...

BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-st...

Fridlich(Ram),Annamalai(Devi),Roy(Rohini),... DNA Repair (Amst) 2015-09-04

...BRCA1-BRCA2 pathway. These DSB resulted in an increase in chromatid-type aberrations, which are characteristic for BRCA1...

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

Apostolou(Paraskevi),Fostira(Florentia),Pa... Cancer Genet 2015-08-06

...BRCA1 founder and recurrent mutations. The CHEK2 c.1100delC mutation was detected in 0.16% (4 of 2,408) of females, all ...

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module an...

Blanco(Ignacio),Kuchenbaecker(Karoline),Cu... PLoS One 2015-12-22

...BRCA1 or BRCA2 mutation carriers. Forty-one single nucleotide polymorphisms (SNPs) were genotyped in 15,252 BRCA1 and 8,...

[Genetical aspects of surgical treatment in patients with hereditary breast c...

Bit-Sava(E M) Vestn Khir Im I I Grek 2015-05-26

...BRCA1 and BRCA2 presented. Recommendations to surgical treatment of hereditary breast cancer are considered as a very di...

Gene promoter methylation and DNA repair capacity in monozygotic twins with d...

Ottini(Laura),Rizzolo(Piera),Siniscalchi(E... Mutat Res Genet Toxicol Env... 2015-05-26

...BRCA1 and PALB2) was assessed in the same batches of cells isolated for previous studies, using the methylation-sensitiv...

The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro.

Chen(Mei-Chuan),Zhou(Bingsen),Zhang(Keqian... Mol Pharmacol 2015-07-07

...BRCA1 cells, suggesting that BRCA1 plays a crucial role in repairing and recovering drug-induced DNA damage by recruitin...

Effects of Radiation Therapy on Breast Epithelial Cells in BRCA1/2 Mutation C...

Chiang(Huai-Chin),Elledge(Richard),Larson(... Breast Cancer (Auckl) 2015-06-08

...BRCA1 and BRCA2 mutations have significantly elevated risk of developing breast and ovarian cancers. BRCA1-associated br...

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