...BRCA1 deficiency is associated with the downregulation of FOXA1 expression. Knockdown of BRCA1 resulted in the downregul...
...BRCA1 mutations preferentially lead to breast cancer whereas mutations compromising mismatch repair drive colon cancer i...
...BRCA1/2 mutations. Furthermore, patients with tumors with NER alterations had similar OS and PFS as BRCA1/2-mutated pati...
...BRCA1 and p53 tumor suppressor expression, in support of further therapeutic research in this field.
BRCA1 and BRCA2 genes are critical in homologous recombination DNA repair and have been implicated in familial breast an...
...BRCA1 germline mutation carriers (approximately 80%), and approximately 11-16% of all TNBCs harbor BRCA1 or BRCA2 germli...
...BRCA1/2 mutation might be more sensitive for the deleterious effects of ionizing radiation due to an impaired capacity o...
...BRCA1/BRCA2-negative Chinese breast cancer families were screened for germline mutations in DICER1. In addition, 100 unr...
...BRCA1/2 mutation, arise in the fimbria of the fallopian tube. However, the site of origin of sporadic HGSC, which is usu...
...BRCA1 and BRCA2 and in cases of pelvic high-grade serous carcinoma. Data on incidental STICs and clinically occult micro...
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