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Somatic alteration and depleted nuclear expression of BAP1 in human esophagea...

Mori(Takahiro),Sumii(Makiko),Fujishima(Fum... Cancer Sci 2015-12-15

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that is involved in the regulation of cell growth. Recent...

Tumour spectrum in non-BRCA hereditary breast cancer families in Sweden.

Wendt(Camilla),Lindblom(Annika),Arver(Brit... Hered Cancer Clin Pract 2015-06-17

...BRCA1 and BRCA2 in hereditary breast and ovarian cancer syndrome. The genetic background in families with hereditary bre...

Effects of Radiation Therapy on Breast Epithelial Cells in BRCA1/2 Mutation C...

Chiang(Huai-Chin),Elledge(Richard),Larson(... Breast Cancer (Auckl) 2015-06-08

...BRCA1 and BRCA2 mutations have significantly elevated risk of developing breast and ovarian cancers. BRCA1-associated br...

Ten modifiers of BRCA1 penetrance validated in a Norwegian series.

Heramb(Cecilie),Ekstrøm(Per Olaf),Tharmara... Hered Cancer Clin Pract 2015-06-08

...BRCA1 penetrance. The aim of this study was to validate these reports in a special cohort of Norwegian BRCA1 mutation ca...

Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identifi...

Brookes(Clare),Lai(Stella),Doherty(Elaine)... Sultan Qaboos Univ Med J 2015-06-08

...BRCA1 and BRCA2 genes. Pathogenic mutations in the BRCA1 and BRCA2 genes lead to an increased risk of developing breast,...

Class I histone deacetylase inhibitors inhibit the retention of BRCA1 and 53B...

Fukuda(Takayo),Wu(Wenwen),Okada(Maiko),Mae... Cancer Sci 2015-10-27

...BRCA1 and BARD1 as well as 53BP1 and RIF1, whereas UNC0638 suppresses IRIF formation of BRCA1 and BARD1 but not 53BP1 an...

Association between cytosolic expression of BRCA1 and metastatic risk in brea...

Santivasi(W L),Wang(H),Wang(T),Yang(Q),Mo(... Br J Cancer 2015-10-14

...BRCA1 has been extensively studied for its role as a tumour-suppressor protein, the role of BRCA1 subcellular localisati...

Deciphering the BRCA1 Tumor Suppressor Network.

Jiang(Qinqin),Greenberg(Roger A) J Biol Chem 2015-10-15

...BRCA1 tumor suppressor protein is a central constituent of several distinct macromolecular protein complexes that execut...

Nicotinamide adenine dinucleotide (NAD) may affect DNA methyltransferase 1 th...

Fang(Yuan-Yuan),Bi(Fang-Fang),Zhou(Yi-Ming... Am J Cancer Res 2015-06-05

...BRCA1-mutated ovarian cancer cells. In contrast, DNMT1 levels are not affected by increasing NAD levels in BRCA1-mutated...

Selective recruitment of host factors by HSV-1 replication centers.

Lang(Feng-Chao),Li(Xin),Vladmirova(Olga),L... Dongwuxue Yanjiu 2015-10-15

...BRCA1 and host antiviral protein SP100. Importantly, we found that ATM kinase was needed for the recruitment of CTCF to ...

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